文献类型：期刊文献

英文题名：Clinical efficacy and safety of robotic retroperitoneal lymph node dissection for testicular cancer: a systematic review and meta-analysis

作者：Yuan, Yacheng[1,2];Zhang, Dawei[3];Ning, Yiping[1,2];Luo, Hengfeng[1,2];Qiu, Xiaolong[1,2];Tan, Yangyang[1,2];Li, Yuxiang[1,2];Yang, Xukai[1,2]

第一作者：Yuan, Yacheng

通信作者：Yang, XK[1];Yang, XK[2]

机构：[1]940 Hosp Joint Logist Support Force Chinese PLA, Dept Urol, Lanzhou, Peoples R China;[2]Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China;[3]Cent Hosp Gansu Prov, Dept Urol, Lanzhou, Peoples R China

第一机构：940 Hosp Joint Logist Support Force Chinese PLA, Dept Urol, Lanzhou, Peoples R China

通信机构：[1]corresponding author), 940 Hosp Joint Logist Support Force Chinese PLA, Dept Urol, Lanzhou, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China.|[10735]甘肃中医药大学;

年份：2023

卷号：13

外文期刊名：FRONTIERS IN ONCOLOGY

收录：;Scopus(收录号：2-s2.0-85181481954);WOS:【SCI-EXPANDED(收录号:WOS:001134263600001)】；

基金：The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the Natural Science Foundation of Gansu Province (No. 18JR3RA405); Natural Science Foundation of Gansu Province (No. 21JR11RA008); and Innovation and Entrepreneurship Talent Project of Lanzhou (No. 2021-RC-106).

语种：英文

外文关键词：retroperitoneal lymph node dissection; robotics; R-RPLND; testicular cancer; meta-analysis

摘要：Background: Retroperitoneal lymph node dissection (RPLND) is an effective treatment for testicular tumors. In recent years, with the development of robotics, many urological procedures performed via standard laparoscopy have been replaced by robots. Our objective was to compare the safety and efficacy of robotic retroperitoneal lymph node dissection (R-RPLND) versus Non-robotic retroperitoneal lymph node dissection (NR-RPLND) in testicular cancer.Methods: Pubmed, Embase, Scopus, Cochrane Library, and Web of Science databases were searched for literature on robotic surgery for testicular germ cell tumors up to April 2023. The statistical and sensitivity analyses were performed using Review Manager 5.3. Meta-analysis was performed to calculate mean difference (MD), odds ratio(OR), and 95% confidence interval (CI) effect indicators.Results: Eight studies with 3875 patients were finally included in this study, 453 with R-RPLND and 3422 with open retroperitoneal lymph node dissection (O-RPLND)/laparoscopic retroperitoneal lymph node dissection (L-RPLND). The results showed that R-RPLND had lower rates of intraoperative blood loss (MD = -436.39; 95% CI -707.60 to -165.19; P = 0.002), transfusion (OR = 0.06; 95% CI 0.01 to 0.26; P = 0.0001), total postoperative complication rates (OR = 0.39; 95% CI 0.21 to 0.70; P = 0.002), and length of stay (MD=-3.74; 95% CI -4.69 to -2.78; P<0.00001). In addition, there were no statistical differences between the two groups regarding perioperative and oncological outcomes regarding total operative time, the incidence of postoperative complications grade >= III, abnormal ejaculation rate, lymph node yield, and postoperative recurrence rate.Conclusions: The R-RPLND and O-RPLND/L-RPLND provide safe and effective retroperitoneal lymph node dissection for testicular cancer. Patients with R-RPLND have less intraoperative bleeding, shorter hospitalization period, fewer postoperative complications, and faster recovery. It should be considered a viable alternative to O-RPLND/L-RPLND.