文献类型：期刊文献

英文题名：COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis

作者：Li, Long-quan[1,2,3];Huang, Tian[1,2,3];Wang, Yong-qing[4];Wang, Zheng-ping[5];Liang, Yuan[1,2,3];Huang, Tao-bi[1,2,3];Zhang, Hui-yun[1,2,3];Sun, Weiming[6];Wang, Yuping[2,3]

第一作者：Li, Long-quan

通信作者：Sun, WM[1];Wang, YP[2]

机构：[1]Lanzhou Univ, Clin Med Sch 1, Lanzhou, Peoples R China;[2]Lanzhou Univ, Hosp 1, Depat Gastroenterol, Lanzhou, Peoples R China;[3]Lanzhou Univ, Hosp 1, Key Lab Gastrointestinal Dis Gansu Prov, Lanzhou, Peoples R China;[4]Gansu Prov Hosp, Day Diagnost Ctr, Lanzhou, Peoples R China;[5]Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou, Peoples R China;[6]Lanzhou Univ, Hosp 1, Dept Endocrinol, 1 West Donggang Rd, Lanzhou 730000, Peoples R China

第一机构：Lanzhou Univ, Clin Med Sch 1, Lanzhou, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Hosp 1, Dept Endocrinol, 1 West Donggang Rd, Lanzhou 730000, Peoples R China;[2]corresponding author), Lanzhou Univ, Hosp 1, Dept Gastroenterol, Key Lab Gastrointestinal Dis Gansu Prov, 1 West Donggang Rd, Lanzhou 730000, Gansu, Peoples R China.

年份：2020

卷号：92

期号：6

起止页码：577

外文期刊名：JOURNAL OF MEDICAL VIROLOGY

收录：;Scopus(收录号：2-s2.0-85082667577);WOS:【SCI-EXPANDED(收录号:WOS:000526462000013)】；

语种：英文

外文关键词：2019-nCoV; clinical characteristics; COVID-19; discharge rate; fatality rate; meta-analysis

摘要：The aim of this study was to analyze the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help. The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate and fatality rate with a single-arm meta-analysis. The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). Minor symptoms include headache or dizziness (12.1%), diarrhea (4.8%), nausea and vomiting (3.9%). The results of the laboratory showed that the lymphocytopenia (64.5%), increase of C-reactive protein (44.3%), increase of lactic dehydrogenase (28.3%), and leukocytopenia (29.4%) were more common. The results of single-arm meta-analysis showed that the male took a larger percentage in the gender distribution of COVID-19 patients 60% (95% CI [0.54, 0.65]), the discharge rate of COVID-19 patients was 52% (95% CI [0.34,0.70]), and the fatality rate was 5% (95% CI [0.01,0.11]).