文献类型：期刊文献

英文题名：Acute myocardial infarction with ventricular septal rupture: Clinical characteristics, prognosis factors, and treatment strategies

作者：Zu, Jian[1];Cheng, Lu[2];Lu, Jing-Jing[3];Xu, Hui;Zhang, Rong[3];Ye, Xue-Rui[2];Qiao, Qian[2];Zhang, Li-Hong[2];Zhang, Hao-Ling[4];Zhang, Jing-Jing[2]

第一作者：Zu, Jian

通信作者：Zhang, JJ[1];Zhang, HL[2]

机构：[1]Gansu Univ Chinese Med, Lanzhou 730000, Gansu, Peoples R China;[2]Chinese Acad Med Sci, Fuwai Yunnan Hosp, Dept Cardiovasc Med, 88 East Kunming Rd, Kunming 650000, Yunnan, Peoples R China;[3]Gansu Univ Chinese Med, Sch Tradit Chinese & Western Med, Lanzhou 730000, Gansu, Peoples R China;[4]Univ Sains Malaysia, Adv Med & Dent Inst, Dept Biomed Sci, George Town 13200, Malaysia

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Chinese Acad Med Sci, Fuwai Yunnan Hosp, Dept Cardiovasc Med, 88 East Kunming Rd, Kunming 650000, Yunnan, Peoples R China;[2]corresponding author), Univ Sains Malaysia, Adv Med & Dent Inst, Dept Biomed Sci, George Town 13200, Malaysia.

年份：2025

卷号：17

期号：7

外文期刊名：WORLD JOURNAL OF CARDIOLOGY

收录：Scopus(收录号：2-s2.0-105011622283);WOS:【ESCI(收录号:WOS:001538523800007)】；

基金：Supported by Science and Technology Department of Yunnan Province-Kunming Medical University, Kunming Medical Joint Special Project-Surface Project, China, No. 202401AY070001-164; and Yunnan Provincial Department of Science and Technology Science and Technology Plan Project-Major Science and Technology Special Projects, No. 202405AJ310003.

语种：英文

外文关键词：Acute myocardial infarction with ventricular septal rupture; Clinical characteristics; Prognostic factors; Surgical repair; Closure of ventricular septal defect through vascular or hybrid surgery; Mechanical cycle support

摘要：This review comprehensively examines acute myocardial infarction with ventricular septal rupture (VSR), a rare yet lethal complication. We analyze its epidemiological, pathophysiological, clinical, and therapeutic aspects, emphasizing innovative strategies like bioabsorbable occluders and tissue engineering to reduce complications and improve prognosis. The integration of artificial intelligence and big data analytics for treatment decision-making and personalized surgical timing models is highlighted as transformative. Our analysis underscores the need for early diagnosis and tailored interventions, proposing future research directions in molecular mechanisms, multidisciplinary collaboration, and technology integration. These innovations promise to enhance VSR management and extend to other cardiovascular diseases, heralding a new era of precision and regenerative cardiovascular medicine.