文献类型：期刊文献

中文题名：基于肠道菌群探讨健脾益胃法干预胃癌化疗后的新视角

英文题名：A new perspective of invigorating spleen and benefiting stomach intervention for gastric cancer after chemotherapy based on intestinal flora

作者：王淼[1];金娟[1];张志明[2];王功臣[2];李高勤[1]

第一作者：王淼

机构：[1]甘肃中医药大学,甘肃兰州730000;[2]甘肃中医药大学附属医院肿瘤科,甘肃兰州730000

第一机构：甘肃中医药大学

年份：2021

卷号：12

期号：6

起止页码：34

中文期刊名：医学争鸣

外文期刊名：Negative

基金：甘肃省中西医结合肿瘤临床医学研究中心课题(18JR2FA001)。

语种：中文

中文关键词：胃癌;肠道菌群;脾胃;肠

外文关键词：gastric cancer;intestinal flora;spleen and stomach;intestine

摘要：胃癌是全球高死亡率的癌症之一,我国的胃癌发病率和死亡例数均居全球首位。研究发现,肠道微生态失调与胃癌关系密切且相互影响,正常的肠道菌群能增强机体的免疫力,发挥抗肿瘤作用,肠道菌群失调后,致病菌会促进肿瘤的发生发展。中医认为,脾胃为后天之本,脾胃功能强健则邪不易入侵,反之亦然,这与肠道菌群功能十分相似。本文以中医脾胃理论与肠道菌群的关系为出发点,探讨健脾益胃法干预胃癌化疗后肠道菌群变化的作用机制,为胃癌及胃肠道其他肿瘤的治疗开拓新思路,以提供更加行之有效的治疗方案。
Gastric cancer is one of the cancers with high mortality in the world.The incidence and death cases of gastric cancer in China rank first in the world.It is found that intestinal microecological disorder is closely related to gastric cancer and influences each other.Normal intestinal flora can enhance immunity and play an anti-tumor role.After intestinal flora disorder,pathogenic bacteria can promote the occurrence and development of tumors.Traditional Chinese medicine believes that the spleen and stomach are the foundation of acquired health,that is,if the spleen and stomach function is strong,evil is not easy to invade,and vice versa,which is very similar to the intestinal flora function.Based on“spleen-stomach-intestine axis”,starting from the relationship between spleen-stomach theory of traditional Chinese medicine and intestinal flora,this paper discusses the action mechanism of invigorating spleen and benefiting stomach method to interfere with intestinal flora changes after chemotherapy for gastric cancer,so as to open up new ideas for the treatment of gastric cancer and other gastrointestinal tumors and provide more effective treatment schemes.