文献类型：期刊文献

英文题名：Computational fluid dynamics analysis of intracranial aneurysms treated with flow diverters: A case report

作者：Zhang, H.[1];Li, L.[2];Miao, F.[3];Yu, J.[4];Zhou, B.[1];Pan, Y.[1]

第一作者：Zhang, H.

通信作者：Pan, Y[1]

机构：[1]Lanzhou Univ, Dept Neurosurg, Hosp 2, 80 Cuiyingmen Rd, Lanzhou 730030, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Sch Clin Med, Lanzhou 730030, Peoples R China;[3]Hexi Univ, Dept Neurosurg, Zhangye Peoples Hosp, Zhangye 734000, Peoples R China;[4]Lanzhou Univ Technol, Coll Petr & Chem Engn, Lanzhou 730050, Peoples R China

第一机构：Lanzhou Univ, Dept Neurosurg, Hosp 2, 80 Cuiyingmen Rd, Lanzhou 730030, Gansu, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Dept Neurosurg, Hosp 2, 80 Cuiyingmen Rd, Lanzhou 730030, Gansu, Peoples R China.

年份：2022

卷号：68

期号：2

起止页码：235

外文期刊名：NEUROCHIRURGIE

收录：;Scopus(收录号：2-s2.0-85106231269);WOS:【SCI-EXPANDED(收录号:WOS:000784208800017)】；

基金：The Cuiying Science and Technology fund of Lanzhou University Second Hospital (CY2018-MS16).

语种：英文

外文关键词：Aneurysms; Stent model; Flow diverter; Pressure; Velocity

摘要：Introduction. - Intracranial aneurysms (IAs) are localized dilatations of intracranial arteries due to weaknesses of the endothelial layer. IAs may be treated by flow diverters (FDs), alternatively to stents and coils combination. FD is a method for the treatment of IAs especially for large, wide-necked or fusiform aneurysms. In this case report, we described a 65-year-old woman with IA who were treated by FD. Case presentation. - A 65-year-old woman was diagnosed with a giant aneurysm at the posterior inferior cerebellar artery segment of the left internal carotid artery. Then based on the computed tomography data of this woman, aneurysm vascular stent model was constructed before and after FD, and internal pressure, velocity, wall shear stress (WSS) of aneurysms were determined by CFD analysis. Standard boundary conditions were applied. It was found that a single FD stent and double FD stents decreased the blood flow and WSS of aneurysm. The effect of single FD stent + 30% filling on blood flow was more obvious, but the aneurysm rupture was caused by excessive coil packing. So, a single stent + 10% coil packing rate was the best option for treating aneurysms. Conclusions. - CFD analysis for flow velocity and WSS have protection on aneurysms. (c) 2021 Elsevier Masson SAS. All rights reserved.