文献类型：期刊文献

英文题名：Case Report: Case of Wernicke's encephalopathy complicated by postoperative gastroparesis following sigmoid colon malignant tumor surgery with a literature review

作者：Qian, Zhengpeng[1,2];Wu, Dewang[1];Zhu, Chengzhang[3];Xu, Shiyun[2];Du, Binbin[1,3];Li, Jingjing[1]

第一作者：Qian, Zhengpeng

通信作者：Li, JJ[1]

机构：[1]Gansu Prov Peoples Hosp, Gansu Prov Clin Res Ctr Anorectal Dis, Dept Anorectal Surg, Lanzhou, Gansu, Peoples R China;[2]Gansu Univ Tradit Chinese Med, Clin Med Coll 1, Lanzhou, Gansu, Peoples R China;[3]Lanzhou Univ, Clin Med Coll 1, Lanzhou, Gansu, Peoples R China

第一机构：Gansu Prov Peoples Hosp, Gansu Prov Clin Res Ctr Anorectal Dis, Dept Anorectal Surg, Lanzhou, Gansu, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Peoples Hosp, Gansu Prov Clin Res Ctr Anorectal Dis, Dept Anorectal Surg, Lanzhou, Gansu, Peoples R China.

年份：2026

卷号：16

外文期刊名：FRONTIERS IN ONCOLOGY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001675849100001)】；

基金：The author(s) declared that financial support was received for this work and/or its publication. Lanzhou Science and Technology Program: No. 2023-2-116; No. 2022-5-70;No. 2022-5-51 Gansu Provincial Department of Education: Excellent Graduate Student "Innovation Project": No. 2025CXZX-946, and Gansu Provincial Health Industry Project (No. GSWSKY2024-12).

语种：英文

外文关键词：gastroparesis; postoperative complications; sigmoid colon malignant tumor; vitamin B1; Wernicke's encephalopathy

摘要：Objective To explore the pathogenesis, clinical characteristics, and key points of the diagnosis and treatment of postoperative gastroparesis (POG) complicated by Wernicke's encephalopathy (WE) after sigmoid colon malignant tumor resection so as to improve the understanding of Wernicke's encephalopathy occurring after gastrointestinal surgery.Methods The clinical data of a patient who developed WE due to POG and prolonged fasting following sigmoid colon cancer resection were retrospectively reviewed, and a comprehensive analysis was conducted in combination with relevant literature.Results The research team retrospectively analyzed a case of intestinal surgery complicated by gastroparesis and long-term fasting, with the patient subsequently presenting with neurological symptoms such as confusion and somnolence. Initially misdiagnosed as an energy deficiency or intracranial lesions, the diagnosis was confirmed by magnetic resonance imaging (MRI) and therapeutic response.Conclusion Gastrointestinal dysfunction and poor nutritional absorption after sigmoid colon resection can induce Wernicke's encephalopathy. Early clinical identification of this disease is particularly important. Postoperative nutritional management and monitoring of neurological symptoms should be emphasized to enable timely intervention.