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益气活血法调控心肌缺血再灌注损伤细胞自噬研究进展     被引量:4

Research Progress in Method of Reinforcing Qi and Activating Blood Circulation in Regulation of Cell Autophagy During Myocardial Ischemia-Reperfusion Injury

文献类型:期刊文献

中文题名:益气活血法调控心肌缺血再灌注损伤细胞自噬研究进展

英文题名:Research Progress in Method of Reinforcing Qi and Activating Blood Circulation in Regulation of Cell Autophagy During Myocardial Ischemia-Reperfusion Injury

作者:颉志英[1];张志明[2];雍文兴[2];王功臣[2];邵向阳[1];宋忠阳[1];梁艳[2]

第一作者:颉志英

机构:[1]甘肃中医药大学,甘肃兰州730000;[2]甘肃中医药大学附属医院,甘肃兰州730000

第一机构:甘肃中医药大学

年份:2020

卷号:27

期号:12

起止页码:130

中文期刊名:中国中医药信息杂志

外文期刊名:Chinese Journal of Information on Traditional Chinese Medicine

收录:CSTPCD;;CSCD:【CSCD_E2019_2020】;

基金:国家自然科学基金(81660730)。

语种:中文

中文关键词:益气活血法;心肌缺血再灌注;自噬;综述;

外文关键词:method of reinforcing qi and activating blood circulation;myocardial ischemia-reperfusion injury;autophagy;review;

摘要:心肌缺血再灌注损伤(MIRI)防治已成为现代医学的研究热点,但其发生机制尚未完全阐明。随着现代医学对该病的深入研究,发现其与细胞自噬密切相关。益气活血类中药可调控心肌细胞自噬蛋白及基因的表达,本文就益气活血类中药对MIRI过程中细胞自噬的影响最新进展进行综述。
The prevention and treatment of myocardial ischemia-reperfusion injury(MIRI)has become a research hotspot in modern medicine,but the mechanism of its occurrence is not completely clear.With the in-depth study of this disease in modern medicine,it is found to be closely related to cell autophagy.TCM with the efficacy of reinforcing qi and activating blood circulation can regulate the expression of autophagy proteins and genes in cardiomyocytes.This article reviewed the latest developments in the effects of TCM with the efficacy of reinforcing qi and activating blood circulation on cell autophagy during MIRI.

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