文献类型：期刊文献

英文题名：Adenosine triphosphate induced cell death: Mechanisms and implications in cancer biology and therapy

作者：Zhang, Hao-Ling[1];Sandai, Doblin[1,8];Zhang, Zhong-Wen[2];Song, Zhi-Jing[3];Babu, Dinesh[4];Tabana, Yasser[4];Dahham, Sabbar Saad[5];Adam, Mowaffaq Adam Ahmed;Wang, Yong[6];Wang, Wei[7];Zhang, Hao-Long[1];Zhao, Rui[3];Barakat, Khaled[4];Harun, Mohammad Syamsul Reza[1];Shapudin, Siti Nurfatimah Mohd[1];Lok, Bronwyn[1]

第一作者：Zhang, Hao-Ling

通信作者：Sandai, D[1]

机构：[1]Univ Sains Malaysia, Adv Med & Dent Inst, Dept Biomed Sci, Kepala Batas 13200, Penang, Malaysia;[2]Gansu Univ Chinese Med, Sch Publ Hlth, Lanzhou 730000, Gansu, Peoples R China;[3]Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou 730000, Gansu, Peoples R China;[4]Univ Alberta, Fac Pharm & Pharmaceut Sci, Edmonton, AB T6G 2E1, Canada;[5]Univ Technol & Appl Sci Rustaq, Dept Sci, Rustaq 329, Oman; San Diego State Univ, Dept Chem Biochem, San Diego, CA 92182 USA;[6]Gansu Univ Chinese Med, Pathol Ctr, Lanzhou 730000, Gansu, Peoples R China;[7]Gansu Univ Chinese Med, Coll Acupuncture Moxibust & Tuina, Lanzhou 730000, Gansu, Peoples R China;[8]Univ Sains Malaysia, Adv Med & Dent Inst, Dept Biomed Sci, Kepala Batas 13200, Penang, Malaysia

第一机构：Univ Sains Malaysia, Adv Med & Dent Inst, Dept Biomed Sci, Kepala Batas 13200, Penang, Malaysia

通信机构：[1]corresponding author), Univ Sains Malaysia, Adv Med & Dent Inst, Dept Biomed Sci, Kepala Batas 13200, Penang, Malaysia.

年份：2023

卷号：14

期号：12

外文期刊名：WORLD JOURNAL OF CLINICAL ONCOLOGY

收录：WOS:【ESCI(收录号:WOS:001135522400005)】；

基金：Supported by National Natural Science Foundation of China, No. 81960877; University Innovation Fund of Gansu Province, No. 2021A-076; Gansu Province Science and Technology Plan (Innovation Base and Talent Plan), No. 21JR7RA561; Natural Science Foundation of Gansu Province, No. 21JR1RA267 and No. 22JR5RA582; Education Technology Innovation Project of Gansu Province, No. 2022A-067; Innovation Fund of Higher Education of Gansu Province, No. 2023A-088; Gansu Province Science and Technology Plan International Cooperation Field Project, No. 23YFWA0005.

语种：英文

外文关键词：Adenosine triphosphate induced cell death; Adenosine triphosphate homeostasis; Mechanism; Cancer signaling pathways; Prognosis and clinical values; Cancer treatment

摘要：Adenosine triphosphate (ATP) induced cell death (AICD) is a critical cellular process that has garnered substantial scientific interest for its profound relevance to cancer biology and to therapeutic interventions. This comprehensive review unveils the intricate web of AICD mechanisms and their intricate connections with cancer biology. This review offers a comprehensive framework for comprehending the multifaceted role of AICD in the context of cancer. This is achieved by elucidating the dynamic interplay between systemic and cellular ATP homeostasis, deciphering the intricate mechanisms governing AICD, elucidating its intricate involvement in cancer signaling pathways, and scrutinizing validated key genes. Moreover, the exploration of AICD as a potential avenue for cancer treatment underscores its essential role in shaping the future landscape of cancer therapeutics.