文献类型：期刊文献

中文题名：不同中医证型脑梗死恢复期患者SPI-Ⅱ再发风险评估及危险因素分析

英文题名：Risk factors analysis and recurrence risk assessment of SPI-Ⅱ in cerebral infarction convalescents with different TCM syndromes

作者：韩艳萍[1,2];刘凯[1]

第一作者：韩艳萍

机构：[1]甘肃中医药大学中西医结合学院,甘肃兰州730101;[2]甘肃中医药大学附属医院神经内科,甘肃兰州730020

第一机构：甘肃中医药大学中西医结合学院

年份：2023

卷号：40

期号：2

起止页码：46

中文期刊名：甘肃中医药大学学报

外文期刊名：Journal of Gansu University of Chinese Medicine

语种：中文

中文关键词：脑梗死恢复期;中医证型;卒中预测工具-Ⅱ评分;风险评估;危险因素

外文关键词：convalescence of cerebral infarction;TCM syndrome type;stroke predictive instrument-Ⅱ(SPI-Ⅱ)score;risk assessment;risk factors

摘要：目的 分析不同中医证型脑梗死恢复期患者卒中预测工具-Ⅱ(SPI-Ⅱ)评分及其危险因素。方法 回顾性分析2017年1月至2021年12月甘肃中医药大学附属医院神经内科住院部收治的415例脑梗死恢复期患者的临床资料,将患者辨证分为肝阳上亢证、痰瘀互结证、气虚血瘀证、痰湿蒙窍证4个证型,运用SPI-Ⅱ分析不同中医证型脑梗死恢复期患者的再发风险及危险因素。结果 415例脑梗死恢复期患者的中医证型以肝阳上亢证为主,占51.08%。肝阳上亢证与痰瘀互结证、痰湿蒙窍证的卒中风险评分比较差异均有统计学意义(P<0.01)。肝阳上亢证再发风险危险度高危与其他3种证型比较差异均有统计学意义(P<0.01)。脑梗死恢复期肝阳上亢证患者SPI-Ⅱ评分与年龄、高血压病、糖尿病、甘油三酯(TG)呈正相关(P<0.01);痰瘀互结证患者SPI-Ⅱ评分与年龄、TG、高血压病呈正相关(P<0.05或P<0.01);气虚血瘀证患者SPI-Ⅱ评分与年龄、TG呈正相关(P<0.01);痰湿蒙窍证患者SPI-Ⅱ评分与TG呈正相关(P<0.01)。结论 肝阳上亢证是脑梗死患者再发高风险的常见证型,年龄、高血压病、糖尿病、TG是影响SPI-Ⅱ评分分层的主要因素。
Objective To analyze the stroke predictive Instrument-Ⅱ(SPI-Ⅱ) score and its risk factors in cerebral infarction convalescents with different TCM syndromes.Methods The clinical data of 415 convalescents with cerebral infarction admitted to the inpatient department of Neurology, Affiliated Hospital of Gansu University of Chinese Medicine from January 2017 to December 2021 were retrospectively analyzed, and the syndrome differentiation of the patients was divided into four types: hyperactivity of liver-yang, interjunction of phlegm-stasis, qi deficiency and blood stagnation, phlegm-dampness covering orifices.SPI-Ⅱ was used to analyze the recurrence risk and risk factors of cerebral infarction convalescents with different TCM syndromes.Results In 415 cases of cerebral infarction convalescents, the main TCM syndrome type was hyperactivity of liver-yang, accounting for 51.08%.There were statistically significant differences in stroke risk scores between the syndrome of hyperactivity of liver-yang and the other two syndromes, namely, interjunction of phlegm-stasis and phlegm-dampness covering orifices(P<0.01).There was statistical significance in the high recurrence risk of hyperactivity of liver-yang compared with the other three syndrome types(P<0.01). SPI-Ⅱ score of cerebral infarction convalescents with hyperactivity of liver-yang syndrome were positively correlated with age, hypertension, diabetes and triglyceride(TG)(P<0.01).SPI-Ⅱ score of convalescents with phlegm-stasis interjunction syndrome was positively correlated with age, TG and hypertension(P<0.05 or P<0.01).The score of SPI-Ⅱ in convalescents with qi deficiency and blood stagnation was positively correlated with age and TG(P<0.01).There was a positive correlation between SPI-Ⅱ score and TG in patients with phlegm-dampness covering orifices syndrome(P<0.01).Conclusion The syndrome of hyperactivity of liver-yang is common type of high risk of recurrence in patients with cerebral infarction. Age, hypertension, diabetes and TG are the main factors affecting SPI-Ⅱ score stratification.