文献类型：期刊文献

中文题名：正交试验法优选于氏萎胃宁提取工艺

英文题名：Selection of Optimum Extraction Process for YSWWN by Orthogonal Design

作者：魏舒畅[1];邓沂[1];包旭宏[2];师霞[1]

第一作者：魏舒畅

机构：[1]甘肃中医学院,甘肃兰州730000;[2]甘肃奇正藏药有限公司,甘肃兰州730000

第一机构：甘肃中医药大学

年份：2004

卷号：11

期号：4

起止页码：318

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2011_2012】；

基金：甘肃省卫生厅资助项目(QSO12-C33-27)

语种：中文

中文关键词：正交试验法;氏萎胃宁;提取工艺;中医;重复性试验

外文关键词：orthogonal design;Paeoniflorin;YSWWN;extraction process

摘要：目的 建立于氏萎胃宁处方中提取药材的提取工艺。方法 采用正交实验,考察不同条件下芍药苷的提取量,以确定于氏萎胃宁的最佳提取工艺。结果 筛选出的最佳提取方法为A2B2C3D2,即乙醇浓度55%,溶剂用量18倍,每次提取1.5h,提取2次最佳。结论 乙醇浓度、提取时间、提取次数、溶剂倍数对提取结果均有显著影响。
Objective To establish the optimum extraction process for YSWWN. Methods The extraction process was studied by orthogonal design with the extract yeild of Paeoniflorin content as markers. Results The optimum extraction process was adding 18 times amont of 55% alcohol, refluxing and extracting for 2 times, 1.5h each time. The extraction process could raise the yield of Paeoniflorin content. Conclusion This extraction process shows higher yeild of Paeoniflorin content, good stability and is available for industrial production.