文献类型：期刊文献

英文题名：A highly selective chemosensor for Al³⁺ based on 2-oxo-quinoline-3-carbaldehyde Schiff-base

作者：Zhang, Ke[1,2];Yang, Zheng-yin[1,2];Wang, Bao-dui[1,2];Sun, Shao-Bo[3];Li, Ying-Dong[3];Li, Tian-rong[1,2];Liu, Zeng-chen[4];An, Jun-mei[1,2]

第一作者：Zhang, Ke

通信作者：Yang, ZY[1]

机构：[1]Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China;[2]Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China;[3]Gansu Univ Tradit Chinese Med, Inst Integrated Tradit & Western Med, Lanzhou 730000, Peoples R China;[4]Zhoukou Normal Univ, Dept Chem, Zhoukou 466001, Peoples R China

第一机构：Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China.

年份：2014

卷号：124

起止页码：59

外文期刊名：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000334130500009)】；

基金：The work was supported by the National Natural Science Foundation of China (81171337), the NCET (13-0262) and the Fundamental Research Funds for the Central Universities (lzujbky-2013-56).

语种：英文

外文关键词：Fluorescence chemosensors; Sensitivity and selectivity; Quinoline derivatives; Detection limit; Bioactivity of Al3+ in living cells

摘要：A new Schiff-base ligand (1) with good fluorescence response to Al3+, derived from 2-oxo-quinoline-3-carbaldehyde and nicotinic hydrazide, had been synthesized and investigated in this paper. Spectroscopic investigation revealed that the compound I exhibited a high selectivity and sensitivity toward Al(III) ions over other commonly coexisting metal ions in ethanol, and the detection limit of Al3+ ions is at the parts per billion level. The mass spectra and Job's plot confirmed the 1:1 stoichiometry between 1 and Al3+. Potential utilization of 1 as intracellular sensors of Al3+ ions in human cancer (HeLa) cells was also examined by confocal fluorescence microscopy. (C) 2013 Elsevier B.V. All rights reserved.