文献类型：期刊文献

英文题名：Comparative clinical outcomes of different therapies for traumatic meniscal tears in adults A protocol for systematic review and network meta-analysis

作者：Hou, Jun-Hu[1];Gong, Yan-Long[1];Ma, Ping[1];Chen, Xin[1];Dong, Wan-Tao[1];Liu, Jian-Jun[1];Liu, Bao-Jian[1];Zhang, Chun-Mu[1]

第一作者：侯军虎

通信作者：Zhang, CM[1]

机构：[1]Gansu Univ Tradit Chinese Med, Dept Sports Med, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学第二附属医院

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Dept Sports Med, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730000, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2022

卷号：101

期号：2

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85123567710);WOS:【SCI-EXPANDED(收录号:WOS:000742407900053)】；

基金：This work was supported by the Natural Science Foundation of Gansu Province (No. 21JR7RA585).

语种：英文

外文关键词：different therapies; network meta-analysis; protocol; systematic review; traumatic meniscal tears

摘要：Background: Meniscus tears are usually classified as degenerative or traumatic tears according to their pathogenesis. At present, traumatic meniscal tears are generally believed to have high healing potential. In recent years, multiple treatments have been described for traumatic meniscal tears, such as the inside-out technique, outside-in technique, all-inside technique, biological augmentation of meniscal repair, meniscectomy, and non-surgical treatment. However, the functional recovery of the knee joint and healing of the meniscus after treatment are quite different from the results reported in the literature, which requires more reliable evidence-based medical findings. This study will evaluate evidence from multiple types of research comparing different therapies for traumatic meniscal tears in adults. Methods We will search the EMBASE, Cochrane Library (the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials [CENTRAL], Cochrane Methodology Register), PubMed, Web of Science (Science and Social Science Citation Index), China Knowledge Network, CBM, Wanfang data, and VIP electronic databases from their inception to August 10, 2021, with no language restrictions. We will also manually search Baidu and Google Scholar to identify randomized controlled studies, non-randomized controlled studies, and cohort studies on the treatment of traumatic meniscal tears. Two researchers will independently screen the literature, extract the data, and evaluate the quality of the studies. Software programs, including Microsoft Access, Excel, Stata (Version 15), WinBUGS (Version 1.4.3), and ADDIS (Version 1.16.8), were used to analyze and manipulate the data. Results In this study, the main outcomes were physical function and healing rate, based on the Western Ontario and McMaster Universities Osteoarthritis Index, Lysholm Knee Scoring Scale, Knee Injury and Osteoarthritis Outcome Score, Functional Recovery Scale, and clinical healing rate. The secondary indexes included total cost, cost-effectiveness ratio, incremental cost-effectiveness ratio, Tegner activity scale score, visual analogue scale, numerical rating scale, and meniscal tear complications. Conclusions: This systematic review will provide reliable evidence-based findings for the clinical application of different therapies for traumatic meniscal tears in adults.