文献类型：期刊文献

英文题名：Primary extranodal marginal zone non-hodgkin lymphoma of the prostate: a case report

作者：Gao, Xiaoru[1,2];Wang, Xinru[1,3];Wang, Xiangfei[1,4];Cai, Hongyi[2]

第一作者：Gao, Xiaoru

通信作者：Cai, HY[1]

机构：[1]Gansu Univ Tradit Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China;[2]Gansu Prov Peoples Hosp, Dept Radiotherapy1, Lanzhou, Peoples R China;[3]Gansu Prov Peoples Hosp, Dept Radiotherapy 2, Lanzhou, Peoples R China;[4]Gansu Prov Peoples Hosp, Dept Oncol Surg, Lanzhou, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Prov Peoples Hosp, Dept Radiotherapy1, Lanzhou, Peoples R China.

年份：2026

卷号：16

外文期刊名：FRONTIERS IN ONCOLOGY

收录：;Scopus(收录号：2-s2.0-105032804349);WOS:【SCI-EXPANDED(收录号:WOS:001715363400001)】；

语种：英文

外文关键词：case report; extra-nodal marginal zone-B lymphoma; non-hodgkin lymphoma; prostate; radiation therapy

摘要：This report describes a clinically rare case of early-stage primary extranodal marginal zone B-cell lymphoma of the prostate. A 73-year-old male presented with urinary hesitancy. Physical examination revealed mild prostatic enlargement. Prostate biopsy, immunohistochemistry, and genetic testing strongly suggested mucosa-associated lymphoid tissue (MALT) lymphoma. Bone marrow aspiration indicated no bone marrow involvement. Positron Emission Tomography-Computed Tomography (PET-CT) and Emission Computed Tomography (ECT) scans showed no evidence of involvement in other sites. Ultimately, the patient was definitively diagnosed with primary prostatic MALT lymphoma, Ann Arbor stage IE. He underwent external beam radiation therapy to the prostate, receiving a total dose of 3000 cGy delivered in 15 fractions. During radiotherapy, the patient experienced no significant adverse reactions. Following treatment, urinary obstruction symptoms markedly improved. Follow-up abdominal and urinary tract ultrasound examinations at 1week, 1month, and 4months post-radiotherapy showed marked tumor regression with no signs of recurrence. This report aims to share the treatment experience of this case, hoping to provide insights for clinicians.