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软坚散结、疏肝活血法治疗乳腺增生症的meta分析     被引量:1

Meta-analysis of the Treatment of Hyperplasia of Mammary Glands with Ruanjian Sanjie and Shugan Huoxue

文献类型:期刊文献

中文题名:软坚散结、疏肝活血法治疗乳腺增生症的meta分析

英文题名:Meta-analysis of the Treatment of Hyperplasia of Mammary Glands with Ruanjian Sanjie and Shugan Huoxue

作者:付兆媛[1];蒋虎刚[2];杨碎胜[3];刘凯[2];赵信科[1];李应东[2]

第一作者:付兆媛

机构:[1]甘肃中医药大学附属医院,甘肃兰州;[2]甘肃中医药大学,甘肃兰州;[3]甘肃省肿瘤医院,甘肃兰州

第一机构:甘肃中医药大学第二附属医院

年份:2020

期号:1

起止页码:48

中文期刊名:世界最新医学信息文摘

外文期刊名:World Latest Medicine Information Electronic Version

基金:甘肃省女性乳房健康管理系统的建立与运行(2016-RC-49)。

语种:中文

中文关键词:Meta分析;软坚散结;疏肝活血;乳腺增生症

外文关键词:Meta analysis;Softening and resolving hard masses;Dispersing liver and promoting blood circulation;Breast hyperplasia

摘要:目的基于meta分析手段系统评价软坚散结、疏肝活血法治疗乳腺增生症的临床疗效,为临床治疗乳腺增生症提供理论依据.方法制定检索策略、纳入排除标准、结局指标后进行文献检索并对纳入文献进行筛选、质量评价、资料提取,最后对结局指标进行统计分析.结果(1)内分泌功能调节方面,软坚散结、疏肝活血法治疗乳腺增生症时能够降低血雌激素、催乳素水平并升高孕激素水平,然而对促黄体生成素水平无调节作用;(2)改善临床表现方面,软坚散结、疏肝活血法治疗乳腺增生症时能够减轻疼痛、软化肿块硬度、缩小肿块直径;(3)软坚散结、疏肝活血法治疗乳腺增生症时能够明显提高治疗总有效率.结论软坚散结、疏肝活血法中药治疗乳腺增生症疗效显著,可广泛应用临床治疗乳腺增生症.
Objective To systematically evaluate the clinical efficacy of Ruanjian Sanjie,Shugan Huoxue therapy in the treatment of breast hyperplasia based on meta-analysis,and provide theoretical basis for clinical treatment of breast hyperplasia.Methods After the search strategy,the exclusion criteria and the outcome indicators were formulated,the literature search was carried out,and the included literature was screened,quality evaluated,extracted,and finally the outcome indicators were statistically analyzed.Results(1)In the regulation of endocrine function,Ruanjian Sanjie,Shugan Huoxue therapy can reduce blood estrogen and prolactin levels and increase progesterone levels in the treatment of hyperplasia of mammary glands,but has no regulatory effect on luteinizing hormone levels;(2)To improve clinical manifestations,the treatment of hyperplasia of the liver and the method of resolving liver and promoting blood circulation can alleviate pain,soften the hardness of the mass and reduce the diameter of the mass;(3)Ruanjian Sanjie,Shugan Huoxue therapy can significantly improve the total effective rate of treatment when treating hyperplasia of mammary glands.Conclusion The traditional Chinese medicine of Ruanjian Sanjie,Shugan Huoxue Recipe has significant curative effect on mammary gland hyperplasia and can be widely used in the clinical treatment of breast hyperplasia.

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