文献类型：期刊文献

英文题名：Effects of mindfulness-based therapy for patients with breast cancer: A systematic review and meta-analysis

作者：Zhang, Jun[1];Xu, Rui[1];Wang, Bo[1];Wang, Jinxia[1]

第一作者：张军

通信作者：Zhang, J[1]

机构：[1]Gansu Univ Chinese Med, Sch Nursing, 35 Dingxidong Rd, Lanzhou 730000, Chengguan Distr, Peoples R China

第一机构：甘肃中医药大学护理学院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, 35 Dingxidong Rd, Lanzhou 730000, Chengguan Distr, Peoples R China.|[10735]甘肃中医药大学;

年份：2016

卷号：26

起止页码：1

外文期刊名：COMPLEMENTARY THERAPIES IN MEDICINE

收录：;Scopus(收录号：2-s2.0-84958950935);WOS:【SSCI(收录号:WOS:000378452000002)，SCI-EXPANDED(收录号:WOS:000378452000002)】；

语种：英文

外文关键词：Mindfulness; Breast cancer; Mental health; Quality of life; Systematic review; Meta-analysis

摘要：Objective: To quantify the effects of mindfulness-based therapy (MBT) on physical health, psychological health and quality of life (QOL) in patients with breast cancer. Method: Studies were identified through a systematic search of six electronic databases. Randomized control trials (RCT5) examining the effects of MBT, versus a control group receiving no intervention on physical health, psychological health and QOL in breast cancer patients were included. Two authors independently assessed the methodological quality of included studies using a quality-scoring instrument developed by Jadad et al. and extracted relevant information according to a predesigned extraction form. Data was analysed using the Cochrane Collaboration's Revman5.1. Result: Finally, seven studies involving 951 patients were included. While limited in power, the results of meta-analysis indicated a positive effect of MBT in reducing anxiety [SMD -0.31, 95% CI -0.46 to -0.16, P<0.0001], depression[SMD -1.13, 95% CI -1.85 to -0.41, P = 0.002], fear of recurrence[SMD -0.71,95% CI -1.05 to -0.38, P<0.0001], and fatigue[SMD -0.88, 95% CI -1.71 to -0.05, P = 0.04] associated with breast cancer, and improving emotional well-being [SMD 0.39, 95% CI 0.19-0.58, P = 0.0001], physical function[SMD 0.42, 95% CI 0.19-0.65, P = 0.0004], and physical health [SMD 0.31, 95% CI 0.08-0.54, P = 0.009] in these patients. Although the effects on stress, spirituality, pain and sleep were in the expected direction, they were not statistically significant (P>0.05). Moreover, there is limited evidence from a narrative synthesis that MBT can improve QOL of breast cancer patients. Conclusion: The present data indicate that MBT is a promising adjunctive therapy for patients with breast cancer. Due to some methodological flaws in the literature, further well-designed RCTs with large sample sizes are needed to confirm these preliminary estimates of effectiveness. (C) 2016 Elsevier Ltd. All rights reserved.