文献类型：期刊文献

英文题名：The Therapeutic Effectiveness of Segmental Lung Resection Versus Lobectomy in Patients With Isolated Lung Metastases From Colorectal Cancer: Evidence From a Retrospective Cohort Study

作者：Que, Changhao[1,2];Wang, Qi[1,2];Ye, Zhibo[1,2];Lu, Peiyuan[1];Li, Chengfang[1];Jin, Dacheng[1,2];Wang, Yaping[1,2];Gou, Yunjiu[1,2]

第一作者：Que, Changhao

通信作者：Gou, YJ[1];Gou, YJ[2]

机构：[1]Gansu Univ Chinese Med, Clin Coll 1, Lanzhou, Gansu, Peoples R China;[2]Gansu Prov Hosp, Dept Thorac Surg, Lanzhou, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Clin Coll 1, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Gansu Prov Hosp, Dept Thorac Surg, Lanzhou, Gansu, Peoples R China.|[10735]甘肃中医药大学;

年份：2025

卷号：2025

期号：1

外文期刊名：INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

收录：;Scopus(收录号：2-s2.0-105006913028);WOS:【SCI-EXPANDED(收录号:WOS:001498996900001)】；

基金：The production of this article, including editorial support and open-access fees, was funded by the Gansu Provincial Health Commission Project (Grant no. GSWSKY2020-50), the Gansu Provincial Department of Science and Technology Project (Grant no. 23JRRA1293), and the Hospital Project of Gansu Provincial People's Hospital (Grant no. 21GSSYB-34)r No Statement Availabler No Statement Available

语种：英文

外文关键词：colorectal cancer lung metastasis; comparative study; lobectomy; segmentectomy; solitary metastasis

摘要：Introduction: In patients with solitary pulmonary metastasis from colorectal cancer, surgical resection is considered a standard treatment protocol and is routinely performed in thoracic surgery. However, there is a paucity of studies that delve into the detailed discussion of the efficacy and safety of lobectomy and segmentectomy in the treatment of pulmonary metastatic cancer. Our study retrospectively analyzed the surgical outcomes of 62 patients from a single center and reported the findings. Methods: A retrospective analysis was meticulously conducted on a cohort of 62 patients who underwent either lung segmental resection (n = 31) or lobectomy (n = 31) for isolated lung metastases at the department of thoracic surgery of Gansu Provincial People's Hospital, spanning a decade from September 2015 to September 2024. The surgical data were thoroughly examined, encompassing perioperative details and patient outcomes. Results: Both surgical approaches achieved successful resection of colorectal cancer lung metastases, without any perioperative mortality reported. In comparison to the group undergoing lung segmental resection, the cohort receiving lobectomy exhibited significantly larger tumor diameters (p < 0.001), prolonged operative durations (p < 0.001), increased intraoperative bleeding (p = 0.002), augmented drainage volume on the first postoperative day (p < 0.001), greater total postoperative drainage (p < 0.001), and elevated operative costs (p < 0.001). However, there were no statistically significant differences between the two groups regarding postoperative pain scores (p = 0.755), time to postoperative extubation (p = 0.744), time to postoperative ambulation (p = 0.742), duration of postoperative hospital stay (p = 0.870), lymph node metastasis (p = 0.671), postoperative complications (p = 0.562), survival rate (p = 0.550), recurrence-free survival rate (p = 0.450), and cumulative incidence (p = 0.321). Conclusions: Pulmonary segmentectomy offers superior advantages in terms of operative time, intraoperative blood loss, drainage volume on the first postoperative day, total postoperative drainage volume, and surgical costs.