文献类型：期刊文献

中文题名：中药炮制前后化学成分转化的研究

英文题名：Research on the transformation of chemical components in the processing of traditional Chinese medicine

作者：李东辉[1];吴红伟[2];李国峰[2];宋沁洁[2];李咸慰[2];杨新荣[2];边甜甜[2];李越峰[2]

第一作者：李东辉

机构：[1]甘肃中医药大学附属医院制剂中心,甘肃兰州730000;[2]甘肃中医药大学,甘肃兰州730000

第一机构：甘肃中医药大学第二附属医院

年份：2023

卷号：40

期号：1

起止页码：106

中文期刊名：沈阳药科大学学报

外文期刊名：Journal of Shenyang Pharmaceutical University

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD_E2023_2024】；

基金：国家自然科学基金资助项目(18JR3RA197,81960713,82160750);甘肃省教育厅产业支撑计划项目(2021CYZC-21);甘肃省中药制药工艺工程研究中心开放课题(ZYGY202003);甘肃省科技计划(创新基地与人才计划)基础研究创新群体项目(21JR7RA569)。

语种：中文

中文关键词：中药炮制;减毒;增效;化学成分

外文关键词：traditional Chinese medicine processing;toxicity reduction;efficiency increase;chemical composition

摘要：中药炮制是依据中医药理论,结合药材自身特性,将药材经净、切、蒸、炒、炙等以改变中药化学成分进而达到调整药性、增强疗效、降低毒性的作用。本文作者通过收集相关文献资料,从减毒与增效两方面阐明中药天南星、白果、附子、草乌、斑蝥、远志、蒺藜、黄芪、党参、黄芩等在炮制过程中的成分转化,明确中药饮片经炮制后达到减毒与增效的物质基础,以期为中药的合理应用与现代化研究提供科学参考。
The processing of traditional Chinese medicines is based on the theory of traditional Chinese medicines,combined with the characteristics of medicinal materials,through cleaning,cutting,steaming,stir-frying,broiling and so on to change the chemical composition of traditional Chinese medicine to adjust the properties,enhance the curative effect and reduce the toxicity.In this paper,we collected relevant literatures to elucidate the transformation of the components of traditional Chinese medicines,such as Arisaematis Rhizoma,Ginkgo Semen,Aconm Lateralis Radix Praeparaia,Aconiti Kusnezoffii Radix,Mylabris,Polygalae Radix,Tribuli Fructus,Astragali Radix,Codonopsis Radix and Scutellariae Radix in the process of concoction,and to clarify the material basis for reducing the toxicity and increasing the efficacy of traditional Chinese medicines after concoction,in order to provide scientific reference for the rational application and modernization research of traditional Chinese medicines.