文献类型：期刊文献

英文题名：A Meta-Analysis of Randomized Controlled Trials on Acupuncture for Amblyopia

作者：Yan, Xingke[1];Zhu, Tiantian[1];Ma, Chongbing[1];Liu, Anguo[1];Dong, Lili[1];Wang, Junyan[1]

第一作者：严兴科

通信作者：Yan, XK[1]

机构：[1]Gansu Univ Tradit Chinese Med, Dept Acupuncture & Moxibust, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学针灸推拿学院

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Dept Acupuncture & Moxibust, Dingxi Dong Rd 35, Lanzhou 730000, Peoples R China.|[10735db5df93766a96e5b]甘肃中医药大学针灸推拿学院;[10735]甘肃中医药大学;

年份：2013

卷号：2013

外文期刊名：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE

收录：;Scopus(收录号：2-s2.0-84877960875);WOS:【SCI-EXPANDED(收录号:WOS:000318933600001)】；

基金：This study was supported in part by the National Natural Science Foundation of China (no. 81260560).

语种：英文

摘要：Objective. To assess the evidence of efficacy and safety of acupuncture for amblyopia and analyze the current situation of its clinical setting. Methods. We systemically searched Wanfang, Chongqing Weipu Database for Chinese Technical Periodicals (VIP), China National Knowledge Infrastructure (CNKI), and PubMed. Published randomized controlled trials (RCT) and controlled clinical trials (CCT) that evaluated the effect of acupuncture for amblyopia compared with conventional treatment were identified. The methodological quality of the included trials was assessed based on the Jadad scale. Data synthesis was facilitated using RevMan 5.1. Results. Fourteen trials involving 2662 participants satisfied the minimum criteria for meta-analysis. The evidence showed that the total effective rate of treatment within the group receiving acupuncture was higher than that in conventional group; there were statistically significant differences between groups (polled random effects model (RR) = 1.17, 95% confidence interval (1.11, 1.24), Z = 5.56, P < 0.00001). Conclusion. The total effective rate of acupuncture for amblyopia was significantly superior to conventional treatment, indicating that acupuncture was a promising treatment for amblyopia. However, due to the limited number of CCTs and RCTs, especially those of large sample size and multicenter randomized controlled studies that were quantitatively insufficient, we could not reach a completely affirmative conclusion until further studies of high quality are available.