详细信息
红芪多糖增强LAK细胞对膀胱肿瘤细胞的杀伤作用 被引量:21
Effect of Radix Hedysari Polysaccharide (HPS) Enhancing Cytotoxicity of LAK cell on Bladder Cancer in vitro
文献类型:期刊文献
中文题名:红芪多糖增强LAK细胞对膀胱肿瘤细胞的杀伤作用
英文题名:Effect of Radix Hedysari Polysaccharide (HPS) Enhancing Cytotoxicity of LAK cell on Bladder Cancer in vitro
作者:崔笑梅[1];王志平[1];张志华[1];任远[2];马骏[2];黄正良[2]
第一作者:崔笑梅
机构:[1]兰州医学院第二附属医院;[2]甘肃中医学院药理教研室
第一机构:兰州医学院第二附属医院
年份:1998
卷号:14
期号:2
起止页码:19
中文期刊名:中药药理与临床
外文期刊名:Pharmacology and Clinics of Chinese Materia Medica
收录:CSCD:【CSCD_E2011_2012】;
语种:中文
中文关键词:红芪多糖;膀胱肿瘤;LAK细胞;PBMC;免疫功能;抗肿瘤作用
外文关键词:Radix Hedysari Polysaccharide;(HPS);LAK cell;Bladder cancer;PBMC
摘要:用MTT法观察了红芪多糖(HPS)对LAK细胞的影响,结果表明HPS无明显的促进LAK细胞扩增的作用,但与LAK细胞或PBMC合用可显著增强对膀胱肿瘤细胞株EJ和原代肿瘤细胞的杀伤作用。
To investigate the effect of HPS on bladder cancer line EJ cell proliferation was tested by 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyltetrazolium bromide (MTT) assay.The results showed that HPS hasn't enhanced effect for LAK cell proliferation.When simultaneously applied with HPS cytotoxicity of LAK cell or PBMC were enhanced agaist EJ cell and BTC from the patients.
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