文献类型：期刊文献

英文题名：Sample preparation using deep eutectic solvents in combination with nanomaterials in analytical procedures: A review

作者：Li, Ke[1,2];Chen, Jingyan[1];Kang, Seulgi[1];Lee, Jeongmi[1]

第一作者：李楷;Li, Ke

通信作者：Lee, JM[1]

机构：[1]Sungkyunkwan Univ, Sch Pharm, Suwon 16419, Gyeonggido, South Korea;[2]Gansu Univ Chinese Med, Gansu Pharmaceut Ind Innovat Res Inst, Lanzhou 730000, Gansu, Peoples R China

第一机构：Sungkyunkwan Univ, Sch Pharm, Suwon 16419, Gyeonggido, South Korea

通信机构：[1]corresponding author), Sungkyunkwan Univ, Sch Pharm, Suwon 16419, Gyeonggido, South Korea.

年份：2025

卷号：1337

外文期刊名：ANALYTICA CHIMICA ACTA

收录：;EI(收录号：20245017513963);Scopus(收录号：2-s2.0-85211388391);WOS:【SCI-EXPANDED(收录号:WOS:001397272900001)】；

基金：This research was supported by two research grants (Nos. 2022R1A6A1A03054419 and RS-2023-00208174) funded by the Na-tional Research Foundation of Korea.

语种：英文

外文关键词：Deep eutectic solvent; Nanomaterial; Sample preparation; Nanosorbent; Nanofluid; Extraction technique

摘要：Background: Sample preparation can be a critical stage of analytical procedures that profoundly influences their performance, environmental impact, and overall efficiency. While nanomaterials have revolutionized sample preparation owing to their high surface area-to-volume ratios, tunable surface chemistry, and enhanced adsorption capacities, limitations persist. Researchers have ushered in a new era of efficient sample preparation methodologies that could overcome the limitations of nanomaterials by introducing deep eutectic solvents (DESs), which have unique advantages such as low volatility and toxicity, biodegradability, and tunability. Results: This review comprehensively explores the integration of DESs into nanomaterials in sample preparation methods. The review begins with a brief review of the different types of sample preparation techniques where DESs in combination with nanomaterials are used, including solid-phase extraction, solid-phase microextraction, and liquid-phase microextraction. The review then delves into different classes of nanomaterials depending on the functions of the DESs, that is, the modifier of nanosorbent, desorption or extraction solvent from nanosorbents, and carrier liquid in nanofluid. It further examines the applications of those nanomaterials to the quantitative analysis of a wide range of analytes within complex matrices. Finally, several challenges and concerns are discussed, including the stability, sustainability, and environmental impact of the materials, as well as the design of task-specific DESs. Significance: Unlike previous reviews on DESs used as extraction solvents, this work is the first review of the nanomaterials in which DESs with diverse roles are involved. While addressing the challenges is crucial, the advantages and opportunities offered by the DES-based nanomaterials warrant further investigation for future development in sample preparation.