详细信息

间充质干细胞抗衰老相关疾病的研究进展    

Research progress in anti-aging-related diseases associated with mesenchymal stem cells

文献类型:期刊文献

中文题名:间充质干细胞抗衰老相关疾病的研究进展

英文题名:Research progress in anti-aging-related diseases associated with mesenchymal stem cells

作者:周士燕[1,2];孙海燕[2,3];张亚妮[3];张江明[3];张研[2,3];张茜[2]

第一作者:周士燕

机构:[1]西北民族大学,兰州市730030;[2]中国人民解放军联勤保障部队第九四〇医院血液内科;[3]甘肃中医药大学

第一机构:西北民族大学,兰州市730030

年份:2025

卷号:47

期号:9

起止页码:1531

中文期刊名:河北医药

外文期刊名:Hebei Medical Journal

基金:甘肃省卫生健康行业科研计划项目(编号:GSWSKY2021-044);甘肃省自然科学基金项目(编号:21JRIRA183);西北民族大学中央高校重大需求培育项目(编号:31920220110);联勤保障部队第九四〇医院基础和临床培育项目(编号:2021yxky042)。

语种:中文

中文关键词:间充质干细胞;衰老相关疾病;外泌体

外文关键词:mesenchymal stem cells;aging-related diseases;exosomes

摘要:随着人口老龄化的不断加剧,与衰老相关的疾病也接踵而来,严重影响老年人的身心健康。间充质干细胞(MSCs)因具有强大的增殖与分化潜能,在抗衰老相关疾病中越来越受到关注。本研究对MSCs在衰老相关的疾病如心血管疾病、2型糖尿病、缺血性脑卒中和骨关节炎中的作用机制和临床试验进行综述,可为MSCs在衰老相关疾病中的研究提供一定的理论依据和参考。
With the aging of the population,aging-related diseases also become a hot topic that seriously affect the physical and mental health of the elderly.Mesenchymal stem cells(MSCs)have attracted increasing attention in anti-aging-related diseases due to their strong proliferation and differentiation potential.This paper reviewed the mechanisms of action and clinical trials of MSCs in aging-related diseases like cardiovascular disease,type 2 diabetes mellitus,ischemic stroke and osteoarthritis,which can provide some theoretical bases and references for the study of MSCs in aging-related diseases.

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