文献类型：期刊文献

英文题名：Research Hotspots of Interferon Gamma in the Treatment of Lung Cancer: A Bibliometric Analysis Based on CiteSpace

作者：Lv, Zhen[1];Wu, Jianjun[1]

第一作者：Lv, Zhen

通信作者：Wu, JJ[1]

机构：[1]Gansu Univ Tradit Chinese Med, Lanzhou, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Dept Publ Hlth, Lanzhou, Peoples R China.|[10735]甘肃中医药大学;

年份：2025

外文期刊名：JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

收录：;Scopus(收录号：2-s2.0-85216840575);WOS:【SCI-EXPANDED(收录号:WOS:001407369700001)】；

基金：The authors declare financial support was received for the research, authorship, and/or publication of this article. This research was supported by This work was supported by National Natural Science Foundation of China (NSFC) (Grant no. 82160900).

语种：英文

外文关键词：bibliometrics; interferon-gamma; lung cancer; research status CiteSpace; visualization analysis

摘要：Interferon-gamma (IFN-gamma) is an important cytokine associated with antitumor immunity and has been implicated in the pathogenesis and progression of lung cancer. Nevertheless, no bibliometric analyses have been published in this field to date, and thus we aim to address this gap in knowledge. A search of the Web of Science (WOS) for literature related to the treatment of lung cancer with IFN-gamma was conducted from 2002 to 2024. The extracted information from the included articles was subjected to visual analysis, and network diagrams were generated using software such as CiteSpace and VOSviewer. In total, 589 articles related to the treatment of lung cancer with IFN-gamma were included in WOS between 2002 and 2024. The number of articles and citation frequency generally showed an increasing trend year by year. The United States and the University of California are the countries and institutions with the largest number of articles. The researcher who made the largest contribution to this field was Xin Cai from China (6). The Journal for ImmunoTherapy of Cancer published the largest number of relevant papers in the field (16 papers, IF = 12.469). The research hotspots in the field of immune escape in recent years have been IFN-gamma, mechanism, immune checkpoints, and microtumor inhibitors. The field of IFN-gamma treatment of lung cancer is evolving at a rapid pace. The current research focus within this field is on elucidating the mechanism of IFN-gamma treatment of lung cancer, investigating the role of immune checkpoint inhibitors, and examining the tumor microenvironment and other pertinent topics.