文献类型：期刊文献

英文题名：The efficacy and safety of acupuncture and nicotine replacement therapy for smoking cessation: study protocol for a randomized controlled trial

作者：Wang, Qingsheng[1,2];Dai, Runjing[3];Zhang, Hailiang[3];Jiang, Xiaomei[4];Ma, Xiaojing[4];Zhang, Xiangrong[5];Bao, Shisan[3];Ren, Dong[4];Fan, Jingchun[3]

第一作者：王庆胜

通信作者：Bao, SS[1];Fan, JC[1];Ren, D[2]

机构：[1]Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou 730000, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Pneumol Dept, Affiliated Hosp, Lanzhou 730000, Gansu, Peoples R China;[3]Gansu Univ Chinese Med, Ctr Evidence Based Med, Lab & Simulat Training Ctr, Sch Publ Hlth, Lanzhou 730000, Gansu, Peoples R China;[4]Gansu Gem Flower Hosp, Psychosomat & Sleep Med, Lanzhou 730060, Gansu, Peoples R China;[5]Hlth Ctr Hekou Town, Lanzhou 730060, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Ctr Evidence Based Med, Lab & Simulat Training Ctr, Sch Publ Hlth, Lanzhou 730000, Gansu, Peoples R China;[2]corresponding author), Gansu Gem Flower Hosp, Psychosomat & Sleep Med, Lanzhou 730060, Gansu, Peoples R China.|[10735e9d5e7087247e71b]甘肃中医药大学公共卫生学院;[10735]甘肃中医药大学;

年份：2022

卷号：23

期号：1

外文期刊名：TRIALS

收录：;Scopus(收录号：2-s2.0-85131264814);WOS:【SCI-EXPANDED(收录号:WOS:000806771200013)】；

基金：This study is supported by the Talent Introduction Program of Gansu University of Chinese Medicine [grant number 2016YJRC-01], the Second Batch of Science and Technology Projects from Chengguan District, Lanzhou, Gansu Province, China [grant number 2020-2-11-16], and the University Innovation Capacity Improvement Project in Gansu Province. Sponsor and funders have no further role in the study design; data collection, management, analysis, or interpretation of data; writing reports; or the decision to submit a report for publication.

语种：英文

外文关键词：Acupuncture; Nicotine replacement therapy; Smoking cessation

摘要：Introduction: Tobacco hazard is one of the most serious public health problems, accounting for up to 6 million deaths worldwide p.a. We aim to determine the efficacy and safety of acupuncture and/or nicotine replacement therapy on smoking cessation. Methods: We will recruit 96 participants who are willing to quit smoking by acupuncture and/or nicotine replacement therapy in Chengguan, Xigu and Heping Districts, Lanzhou city, for multicenter randomized, double-blind, double-dummy controlled clinical trial. Following obtained the informed consent forms, all eligible participants will be randomly divided into 4 groups: (1) acupuncture combined with nicotine patch, (2) acupuncture combined with sham nicotine patch, (3) sham acupuncture combined with nicotine patch, and (4) sham acupuncture combined with sham nicotine patch. These participants will be treated with different intervention modalities for 8weeks and then will be followed-up for 8weeks. The SPSS 26.0 software will be applied to analyze the clinical effects and adverse reactions of different intervention measures for smoking cessation. Discussion: This trial is a prospective, pragmatic, randomized, multicenter trial study protocol. The outcomes will illustrate the efficacy and safety of acupuncture and/or nicotine patches for smoking cessation. Provide smokers with a superior smoking cessation program.