文献类型：期刊文献

英文题名：Immediate effects of scalp acupuncture with twirling reinforcing manipulation on hemiplegia following acute ischemic stroke: a hidden association study

作者：Du, Xiao-zheng[1];Bao, Chun-ling[2];Dong, Gui-rong[2];Yang, Xu-ming[3]

第一作者：杜小正

通信作者：Du, XZ[1];Yang, XM[2]

机构：[1]Gansu Univ Chinese Med, Sch Acupuncture & Manipulat, Lanzhou, Gansu, Peoples R China;[2]Shanghai Univ Tradit Chinese Med, Yueyang Hosp Integrated Med, Dept Acupuncture, Shanghai, Peoples R China;[3]Shanghai Univ Tradit Chinese Med, Sch Acupuncture & Manipulat, Shanghai, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Sch Acupuncture & Manipulat, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Shanghai Univ Tradit Chinese Med, Sch Acupuncture & Manipulat, Shanghai, Peoples R China.|[10735]甘肃中医药大学;

年份：2016

卷号：11

期号：5

起止页码：758

外文期刊名：NEURAL REGENERATION RESEARCH

收录：;Scopus(收录号：2-s2.0-84971455436);WOS:【SCI-EXPANDED(收录号:WOS:000378537700023)】；

基金：This work was supported by a grant from the Supporting Program of the "Eleventh Five-year Plan" for Science & Technology Research of China, Ministry of Science and Technology of China, No. 2006BAI12B02; and a grant from the Scientific Research Fund for Talent Introduction in the Gansu University of Chinese Medicine of China, No. 2012-11.

语种：英文

外文关键词：nerve regeneration; traditional Chinese medicine; needling; reinforcing manipulation; hemiplegia due to acute ischemic stroke; immediate effect; association algorithm; artificial neural network algorithm; neurological deficit score; simplified Fugl-Meyer assessment; H-max/M-max; traditional Chinese medicine syndromes; scalp acupoints; neural regeneration

摘要：Data mining has the potential to provide information for improving clinical acupuncture strategies by uncovering hidden rules between acupuncture manipulation and therapeutic effects in a data set. In this study, we performed acupuncture on 30 patients with hemiplegia due to acute ischemic stroke. All participants were pre-screened to ensure that they exhibited immediate responses to acupuncture. We used a twirling reinforcing acupuncture manipulation at the specific lines between the bilateral Baihui (GV20) and Taiyang (EX-HN5). We collected neurologic deficit score, simplified Fugl-Meyer assessment score, muscle strength of the proximal and distal hemiplegic limbs, ratio of the maximal H-reflex to the maximal M-wave (H-max/M-max), muscle tension at baseline and immediately after treatment, and the syndromes of traditional Chinese medicine at baseline. We then conducted data mining using an association algorithm and an artificial neural network backpropagation algorithm. We found that the twirling reinforcing manipulation had no obvious therapeutic difference in traditional Chinese medicine syndromes of "Deficiency and Excess". The change in the muscle strength of the upper distal and lower proximal limbs was one of the main factors affecting the immediate change in Fugl-Meyer scores. Additionally, we found a positive correlation between the muscle tension change of the upper limb and H-max/M-max immediate change, and both positive and negative correlations existed between the muscle tension change of the lower limb and immediate H-max/M-max change. Additionally, when the difference value of muscle tension for the upper and lower limbs was > 0 or < 0, the difference value of H-max/M-max was correspondingly positive or negative, indicating the scalp acupuncture has a bidirectional effect on muscle tension in hemiplegic limbs. Therefore, acupuncture with twirling reinforcing manipulation has distinct effects on acute ischemic stroke patients with different symptoms or stages of disease. Improved muscle tension in the upper and lower limbs, reflected by the variation in the H-max/M-max ratio, is crucial for recovery of motor function from hemiplegia.