文献类型：期刊文献

中文题名：气相色谱-质谱法测定甘肃陇南大红袍花椒挥发油乙酸芳樟酯和芳樟醇含量

英文题名：Determination of linalyl acetate and linalool contents in Volatile oil of Dahongpao Zanthoxylum bungeanum in Longnan by gas chromatography-mass spectrometry

作者：司昕蕾[1,2];张爱霞[1,2];边甜甜[1,2];辛二旦[1,2];牛江涛[1,2];曹瑞[1,2];李越峰[1,2]

第一作者：司昕蕾

机构：[1]甘肃中医药大学药学院,兰州730000;[2]甘肃省中药质量与标准研究重点实验室,兰州730000

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

年份：2019

卷号：35

期号：5

起止页码：468

中文期刊名：中国临床药理学杂志

外文期刊名：The Chinese Journal of Clinical Pharmacology

收录：CSTPCD;;北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

基金：国家自然科学基金资助项目(81460611);教育部科学技术研究重点基金资助项目(212186);甘肃省自然科学基金资助项目(2010:1010RJZA212; 2014:145RJZA076);甘肃省财政厅高校基本科研业务费专项基金资金项目(2013-2);甘肃省中医药管理局科研课题基金资助项目(GZK-2015-57);甘肃省科技支撑计划基金资助项目(1204FKA140);兰州市科技局基金资助项目(2014-1-188);甘肃中医药大学研究生创新基金资助项目(CX2018-27)

语种：中文

中文关键词：甘肃陇南大红袍花椒;花椒挥发油;气相色谱-质谱法

外文关键词：Dahongpao Zanthoxylum bungeanum in Longnan;Volatile oil of Zanthoxylum bungeanum;gas chromatography-mass spectrometry

摘要：目的建立花椒中乙酸芳樟酯、芳樟醇含量测定快速灵敏的检测方法。方法用水蒸气蒸馏法提取陇南大红袍花椒挥发油,以正己烷为稀释剂,用气相色谱-质谱法(GC-MS)分析其乙酸芳樟酯、芳樟醇。结果乙酸芳樟酯在0. 35～1. 50 mg·m L^(-1)内呈良好的线性关系,响应值与浓度的回归方程:y=6×10~8x-1×10~8(R^2=0. 9992)。芳樟醇在0. 32～0. 96 mg·m L^(-1)内呈良好的线性关系,响应值与浓度的回归方程:y=4×10~8x-5×10~7(R^2=0. 9991)。陇南大红袍花椒中乙酸芳樟酯含量为(0. 93±0. 13)%,芳樟醇含量为(1. 07±0. 16)%。结论本文建立的GC-MS方法,具有灵敏、快速、准确的特点,可供陇南大红袍花椒质量控制和化学成分含量测定。
Objective To establish a rapid and sensitive detection method for the determination of acetic acid-linalyl ester and linalool in Zanthoxylum bungeanum gas chromatography-mass spectrometry( GC-MS). Methods The Volatile oil of Dahongpao Zanthoxylum bungeanum in Longnan was extracted by steam distillation. And it’s acetic acid-linalyl ester and linalool were analyzed by GC-MS. Hexane is used as a thinner. Results The concentration of acetic acid-linalyl ester has a good linear relationship in the range of 0. 35-1. 50 mg · m L-1. The regression equation of response value and concentration was: y = 6 × 108 x-1 × 108( R2= 0. 9992). The concentration of Longnan has a good linear relationship in the range of 0. 32-0. 96 mg ·m L-1. The regression equation of response value and concentration was: y = 4 × 108 x-5 ×107( R2= 0. 9991). Conclusion The GC-MS method established is sensitive,rapid and accurate,and can be used for the quality control and chemical composition determination of Dahongpao Zanthoxylum bungeanum in Longnan.