文献类型：期刊文献

英文题名：Adolescent idiopathic scoliosis non-surgical interventions: a systematic review and network meta-analysis of Cobb angle and SRS-22 outcomes

作者：Yang, Shaobo[1];Cai, Feihong[2];Xie, Ruixuan[3];Li, Jing[4];Zhao, Jun[5];Zhang, Chen[6];Hou, Dong[6];Li, Kai[7];Leng, Han[6];Dou, Xiaohui[8];Zhang, Jing[1];Cui, Xiaojuan[6];Wang, Juan[6];Yuan, Xiaoyun[6];Zhang, Haitao[9];Tang, Dezhi[2];Wen, Jiantao[6];Huang, Jin[6]

第一作者：Yang, Shaobo

通信作者：Tang, DZ[1];Wen, JT[2];Huang, J[2]

机构：[1]Gansu Univ Chinese Med, Sch Integrated Chinese & Western Med, Lanzhou, Peoples R China;[2]Shanghai Univ Tradit Chinese Med, Longhua Hosp, Inst Spine Dis, Shanghai, Peoples R China;[3]Wenzhou Med Univ, Sch Ophthalmol & Optometry, Sch Biomed Engn, Wenzhou, Peoples R China;[4]Gansu Prov Hosp Tradit Chinese Med, Dept Spleen & Stomach Dis, Lanzhou, Peoples R China;[5]Gansu Prov Hosp Tradit Chinese Med, Dept Orthoped, Lanzhou, Peoples R China;[6]Gansu Prov Hosp Tradit Chinese Med, Dept Spine Orthoped, Lanzhou, Peoples R China;[7]First Peoples Hosp Longnan, Dept Emergency Surg, Longnan, Peoples R China;[8]Gansu Univ Chinese Med, Sch Clin Chinese Med, Lanzhou, Peoples R China;[9]Guangzhou Univ Chinese Med, Affiliated Hosp 1, Dept Artificial Joint & Knee Surg, Guangzhou, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Shanghai Univ Tradit Chinese Med, Longhua Hosp, Inst Spine Dis, Shanghai, Peoples R China;[2]corresponding author), Gansu Prov Hosp Tradit Chinese Med, Dept Spine Orthoped, Lanzhou, Peoples R China.

年份：2026

卷号：14

外文期刊名：FRONTIERS IN PEDIATRICS

收录：;Scopus(收录号：2-s2.0-105051607243);WOS:【SCI-EXPANDED(收录号:WOS:001884606500001)】；

基金：The author(s) declared that financial support was received for this work and/or its publication. This work was supported by the 2024 Gansu Provincial Talent Program (Grant No. 2024QNTD05), the Natural Science Foundation of the Gansu Provincial Science and Technology Program (Grant No. 22JR5RA632), the Joint Research Fund of the Gansu Provincial Science and Technology Program (Grant No. 23JRRA1529), the Major Research Project for Technological Innovation in the Health Industry of Gansu Province (Grant No. GSWSQNPY2024-03), the Key Project of the Gansu Provincial Joint Research Fund (Grant No. 25JRRA1220), the General Project of the Gansu Provincial Joint Research Fund (Grant No. 25JRRA1224), the Gansu Provincial Disease Prevention and Control Research Projects (Grant Nos. GSJKKY2025-08 and GSJKKY2025-46), and the Gansu Provincial Traditional Chinese Medicine Research Program (Grant No. CZKZ-2025-5).

语种：英文

外文关键词：adolescent idiopathic scoliosis; bracing; Cobb angle; exercise therapy; network meta-analysis; non-surgical treatment; SRS-22

摘要：

Background: Adolescent idiopathic scoliosis (AIS) is a common three-dimensional spinal deformity. Non-surgical interventions are important for controlling curve progression and maintaining quality of life, but their comparative effectiveness remains uncertain.

Objective: To compare the effects of commonly used non-surgical interventions for AIS on Cobb angle and SRS-22 outcomes through a systematic review and network meta-analysis.

Methods: PubMed/MEDLINE, Embase, Web of Science, Cochrane Library, and major Chinese databases were searched from inception to April 4, 2026. Randomized controlled trials (RCTs) comparing non-surgical interventions and reporting Cobb angle or SRS-22 were included for the primary network meta-analysis. Prospective non-randomized studies served as supplementary evidence. Effect sizes were expressed as standardized mean differences (SMDs) with 95% confidence intervals (CIs). Ranking was assessed using SUCRA, interpreted cautiously with heterogeneity and evidence sparsity.

Results: Thirteen comparative studies (709 AIS subjects) were included (10 RCTs, 3 non-randomized). Interventions included Schroth training, bracing, scoliosis-specific exercises, core stabilization, and traditional Chinese medicine rehabilitation. Traditional pairwise meta-analysis showed a pooled SMD of -1.39 (95% CI: -2.20 to -0.59) with high heterogeneity (I-2 = 95.1%). Network ranking suggested that bracing and Schroth-related therapies had a trend toward better short-term Cobb angle control, but most estimates were imprecise and the evidence network was sparse. Evidence on SRS-22 was limited and exploratory.

Conclusion: Some non-surgical interventions may improve Cobb angle in AIS; bracing and Schroth-related therapies show a trend toward relative superiority for short-term Cobb angle control. However, due to sparse networks, high heterogeneity, and potential small-study effects, results should be interpreted cautiously and not solely based on SUCRA rankings. SRS-22 evidence remains insufficient. High-quality RCTs with longer follow-up are needed.