文献类型：期刊文献

英文题名：Comparing the efficacy and safety between femtosecond laser-assisted cataract surgery and conventional phacoemulsification cataract surgery: systematic review and meta-analysis

作者：Song, Xinzhi[1];Li, Ling[2];Zhang, Xuemei[1];Ma, Jianjun[1]

第一作者：Song, Xinzhi

通信作者：Song, XZ[1];Li, L[2]

机构：[1]Gansu Prov Hosp, Dept Ophthalmol, Lanzhou, Peoples R China;[2]Gansu Univ Chinese Med, Gansu Univ, Key Lab Mol Med & Chinese Med Prevent & Treatment, Lanzhou, Peoples R China

第一机构：Gansu Prov Hosp, Dept Ophthalmol, Lanzhou, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, 204 Donggang West Rd, Lanzhou 730000, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, 35 Dingxi East Rd, Lanzhou 730000, Peoples R China.|[10735]甘肃中医药大学;

年份：2025

卷号：60

期号：1

起止页码：e1

外文期刊名：CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE

收录：;Scopus(收录号：2-s2.0-85199771342);WOS:【SCI-EXPANDED(收录号:WOS:001454080900001)】；

基金：Supported by: This work was supported by Gansu Natural Science Foundation (No. 22JR5RA675 to Xuemei Zhang and Xinzhi Song) and the Internal Research Fund project of Gansu Provincial Hospital (No. 21GSSYC-9 to Xinzhi Song) .

语种：英文

摘要：Objective: To investigate the efficacy and safety of femtosecond laser-assisted cataract surgery (FLACS) compared with conventional phacoemulsification cataract surgery (CPCS). Methods: Randomized controlled trials (RCTs) were systematically searched in PubMed, Embase, Cochrane Library, ClinicalTrials.gov, CNKI, and Wanfang. Main outcomes were visual acuity, capsulotomy parameters, effective lens position, and complications. Secondary outcomes included refractive outcomes, intraoperative parameters, and corneal parameters. Results: In total, 41 RCTs involving 9310 eyes were included. There was a statistically significant difference in favour of FLACS over CPCS for uncorrected distance visual acuity at 12 months (mean difference [MD]-0.03; 95% CI-0.05 to-0.01); corrected distance visual acuity at 1 week (MD-0.05; 95% CI-0.07 to-0.02) and 12 months (MD-0.02; 95% CI-0.04 to-0.00); area of capsulotomy at 1 month (MD 4.04 mm(2); 95% CI 3.45-4.64) and 6 months (MD 5.02 mm(2); 95% CI 3.28-6.77); and intraocular lens centroid-pupil centroid distance at 1 week (MD-0.06 mm; 95% CI-0.08 to-0.05), 1 month (MD-0.07 mm; 95% CI-0.09 to-0.06), and 6 months (MD-0.06 mm; 95% CI-0.07 to-0.04). With regard to surgical complications, FLACS was less than CPCS for the incidence of decentred IOL (odds ratio 0.06; 95% CI 0.01-0.24). However, FLACS did not increase the incidence of other intraoperative or postoperative complications except subconjunctival hemorrhage. Conclusions: Both FLACS and CPCS are effective and safe. FLACS achieves better visual outcomes in the early postoperative period and long-term follow-up, accompanied by more accurate capsulotomy and more optimized effective lens position than CPCS. However, difference of visual outcomes was found after middle-term follow-up.