文献类型：期刊文献

中文题名：红芪对油酸型肺损伤大鼠肺泡表面活性物质含量及板层小体的影响

英文题名：Effects of Radix Hedysari on Changes of Pulmonary Surfactant and Osmiophilic Multilamellar Body in Rats with Respiratory Distress Syndrome

作者：白娟[1];黄正良[1];李萍[1]

第一作者：白娟

机构：[1]甘肃中医学院

第一机构：甘肃中医药大学

年份：1997

卷号：13

期号：2

起止页码：26

中文期刊名：中药药理与临床

外文期刊名：Pharmacology and Clinics of Chinese Materia Medica

收录：CSCD:【CSCD_E2011_2012】；

语种：中文

中文关键词：红芪;油酸型肺损伤;肺泡表面活性物质;板层小体

外文关键词：Radix Hedysari;Respiratory distress syndrome;pulmonary surfactant; osmiophilic multilamellar body

摘要：本文用油酸型大鼠呼吸窘迫综合征（ＲＤＳ）模型，研究了红芪水提物（ＨＥ）对其影响的机理。结果表明，ＨＥ能提高大鼠ＲＤＳ的肺泡表面活性物质（ＰＳ），电镜观察发现ＨＥ对大鼠ＲＤＳⅡ型肺泡细胞有保护作用，能促使其恢复产生和释放ＰＳ功能，稳定了细胞内板层小体的结构。
The experimental research on effective mechanism of Radix Hedysari(HE) treated Respiratory Distress Syndrome (RDS) induced by oleic acid were observed. The results showed that HE could increase contents of pulmonary surfactant(PS) in RDS rats. The observed under electronic microscope found that HE could protect Ⅱ type alveolar cells, promote their function of producing and releasing PS recovered,and steady structure of osmiophilic multilamellar body in cells.