文献类型：期刊文献

英文题名：Global prevalence of norovirus gastroenteritis after emergence of the GII.4 Sydney 2012 variant: a systematic review and meta-analysis

作者：Zhang, Pan[1,2];Hao, Cai[1,2];Di, Xie[3];Chuizhao, Xue[4];Jinsong, Li[2];Guisen, Zheng[1];Hui, Liu[3];Zhaojun, Duan[2]

第一作者：Zhang, Pan;张苹;张萍;张鹏

通信作者：Guisen, Z[1];Jinsong, L[2];Zhaojun, D[2];Hui, L[3]

机构：[1]Gansu Univ Tradit Chinese Med, Coll Publ Hlth, Lanzhou, Gansu, Peoples R China;[2]Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Natl Key Lab Intelligent Tracking & Forecasting In, NHC Key Lab Med Virol & Viral Dis, Beijing, Peoples R China;[3]Chengdu Kanghua Biol Prod Co Ltd, Chengdu, Peoples R China;[4]Chinese Ctr Dis Control & Prevent, Chinese Ctr Trop Dis Res, WHO Collaborating Ctr Trop Dis, NHC Key Lab Parasite & Vector Biol,Natl Ctr Int Re, Shanghai, Peoples R China

第一机构：甘肃中医药大学公共卫生学院

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Coll Publ Hlth, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Chinese Ctr Dis Control & Prevent, Natl Inst Viral Dis Control & Prevent, Natl Key Lab Intelligent Tracking & Forecasting In, NHC Key Lab Med Virol & Viral Dis, Beijing, Peoples R China;[3]corresponding author), Chengdu Kanghua Biol Prod Co Ltd, Chengdu, Peoples R China.|[10735e9d5e7087247e71b]甘肃中医药大学公共卫生学院;[10735]甘肃中医药大学;

年份：2024

卷号：12

外文期刊名：FRONTIERS IN PUBLIC HEALTH

收录：;Scopus(收录号：2-s2.0-85198108528);WOS:【SSCI(收录号:WOS:001266996600001)，SCI-EXPANDED(收录号:WOS:001266996600001)】；

基金：The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This study was supported by funding from Beijing Natural Science Foundation (No. L232011), Epidemiological characteristics and economic burden of gastroenteritis caused by gene variation of norovirus in China and National Key Research, and Development Program of China (No. 2021YFC2301000), Research on targeted culture technology of difficult culture and trace pathogens.DAS:The original contributions presented in the study are included in the article/Supplementary material, further inquiries can be directed to the corresponding authors.

语种：英文

外文关键词：norovirus; gastroenteritis; prevalence; meta-analysis; genotype

摘要：Introduction Norovirus is widely recognized as a leading cause of both sporadic cases and outbreaks of acute gastroenteritis (AGE) across all age groups. The GII.4 Sydney 2012 variant has consistently prevailed since 2012, distinguishing itself from other variants that typically circulate for a period of 2-4 years. Objective This review aims to systematically summarize the prevalence of norovirus gastroenteritis following emergence of the GII.4 Sydney 2012 variant. Methods Data were collected from PubMed, Embase, Web of Science, and Cochrane databases spanning the period between January 2012 and August 2022. A meta-analysis was conducted to investigate the global prevalence and distribution patterns of norovirus gastroenteritis from 2012 to 2022. Results The global pooled prevalence of norovirus gastroenteritis was determined to be 19.04% (16.66-21.42%) based on a comprehensive analysis of 70 studies, which included a total of 85,798 sporadic cases with acute gastroenteritis and identified 15,089 positive cases for norovirus. The prevalence rate is higher in winter than other seasons, and there are great differences among countries and age groups. The pooled attack rate of norovirus infection is estimated to be 36.89% (95% CI, 36.24-37.55%), based on a sample of 6,992 individuals who tested positive for norovirus out of a total population of 17,958 individuals exposed during outbreak events. Conclusion The global prevalence of norovirus gastroenteritis is always high, necessitating an increased emphasis on prevention and control strategies with vaccine development for this infectious disease, particularly among the children under 5 years old and the geriatric population (individuals over 60 years old).