文献类型：期刊文献

英文题名：Case report: Severe acute hepatitis in a 22-month-old Chinese boy with Omicron sub-variant BA.2.38

作者：Chen, Xinying[1,2];Hong, Junbin[3];Li, Yuxia[4];An, Caixia[5];Guo, Jianwen[6,7];Yang, Jinghua[1,2]

第一作者：Chen, Xinying

通信作者：Yang, JH[1];Yang, JH[2];Guo, JW[3];Guo, JW[4]

机构：[1]Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Pediat, Guangzhou, Peoples R China;[2]Guangdong Prov Hosp Chinese Med, Xiaorong Luos Renowned Expert Inheritance Studio, Guangzhou, Peoples R China;[3]Guangzhou Univ Chinese Med, Clin Med Coll 2, Guangzhou, Peoples R China;[4]Gansu Univ Chinese Med, Affiliated Hosp, Dept Pediat, Lanzhou, Peoples R China;[5]Gansu Prov Maternal & Child Hlth Hosp, Dept Pediat Cardiol Nephrol Rheumatol & Immunol, Lanzhou, Peoples R China;[6]Guangzhou Univ Chinese Med, Affiliated Hosp 2, State Key Lab Dampness Syndrome Chinese Med, Guangzhou, Peoples R China;[7]Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Neurol, Guangzhou, Peoples R China

第一机构：Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Pediat, Guangzhou, Peoples R China

通信机构：[1]corresponding author), Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Pediat, Guangzhou, Peoples R China;[2]corresponding author), Guangdong Prov Hosp Chinese Med, Xiaorong Luos Renowned Expert Inheritance Studio, Guangzhou, Peoples R China;[3]corresponding author), Guangzhou Univ Chinese Med, Affiliated Hosp 2, State Key Lab Dampness Syndrome Chinese Med, Guangzhou, Peoples R China;[4]corresponding author), Guangzhou Univ Chinese Med, Affiliated Hosp 2, Dept Neurol, Guangzhou, Peoples R China.

年份：2022

卷号：10

外文期刊名：FRONTIERS IN PUBLIC HEALTH

收录：;Scopus(收录号：2-s2.0-85143607452);WOS:【SSCI(收录号:WOS:000894184200001)，SCI-EXPANDED(收录号:WOS:000894184200001)】；

语种：英文

外文关键词：severe acute hepatitis; SARS-CoV-2; Omicron variant; case report; pediatrics

摘要：The etiology of severe acute hepatitis (SAH) in children is various. We describe the first Chinese case of severe acute hepatitis in a 22-month-old boy with the mild illness of Omicron sub-variant BA.2.38. With the application of Compound Glycyrrhizin Injection (CGI), the patient gradually recovered from acute liver injury (ALI). This case highlights the possibility of severe ALI in children with the non-critical illness of SARS-CoV-2. The management of SAH associated with the pandemic presents challenges for clinicians, and follow-up is in need. The method of differential diagnosis using limited laboratory results is of great value to the clinicians.