详细信息
二次正交旋转组合设计法优化赤芍醇提工艺
Quadratic-Orthogonal-Rotation-Combination Design for Optimization of Ethanol Extraction Craft from Radix Paeoniae Rubra
文献类型:期刊文献
中文题名:二次正交旋转组合设计法优化赤芍醇提工艺
英文题名:Quadratic-Orthogonal-Rotation-Combination Design for Optimization of Ethanol Extraction Craft from Radix Paeoniae Rubra
作者:彭晓霞[1];张振巍[1]
第一作者:彭晓霞
机构:[1]甘肃中医学院,甘肃兰州730000
第一机构:甘肃中医药大学
年份:2010
卷号:33
期号:6
起止页码:991
中文期刊名:中药材
外文期刊名:Journal of Chinese Medicinal Materials
收录:MEDLINE(收录号:21049627);CSTPCD;;Scopus(收录号:2-s2.0-79956268444);北大核心:【北大核心2008】;CSCD:【CSCD2011_2012】;PubMed;
语种:中文
中文关键词:赤芍;二次正交旋转组合设计;提取工艺
外文关键词:Radix Paeniae Rubra(RPR); Quadratic-orthogonal-rotation-combination design; Extraction process
摘要:目的:二次正交旋转组合设计法优化赤芍醇提工艺。方法:以芍药苷提取率为指标,乙醇浓度、提取时间、乙醇用量为考察因素,采用二次正交旋转组合设计法优选回流提取工艺条件,并进行预测分析。结果:最优提取工艺为:乙醇浓度73%,提取时间100 min,乙醇用量8.3倍。结论:中心组合设计法具有应用简便、预测性好等优点。
Objective: To optimize the ethanol extraction process of Radix Paeoniae Rubra(RPR) using quadratic-orthogonal-rotation-combination design.Methods: The influential factors were ethanol volume,ethanol concentration and extracting time.The evaluating indicator was the extraction rate of peoniflorin.The quadratic-orthogonal-rotation-combination design was used to optimize the process and the prediction was carried out.Results: The optimum conditions of extraction were 73% ethanol,100 min for extraction,volume of ethanol was 8.3 times.Conclusion: It shows that the optimum model is simple and highly predictive.
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