文献类型：期刊文献

中文题名：超声引导下热消融联合免疫检查点抑制剂治疗肝细胞癌研究进展

英文题名：Progress of ultrasound-guided thermal ablation combined with immune checkpoint inhibitors for treating hepatocellular carcinoma

作者：王菲[1,2];周祖邦[1,2]

第一作者：王菲

机构：[1]甘肃中医药大学研究生院,甘肃兰州730000;[2]甘肃省人民医院超声医学科,甘肃兰州730000

第一机构：甘肃中医药大学党委研究生工作部、研究生院

年份：2019

卷号：16

期号：11

起止页码：700

中文期刊名：中国介入影像与治疗学

外文期刊名：Chinese Journal of Interventional Imaging and Therapy

收录：CSTPCD;;Scopus;北大核心:【北大核心2017】；

语种：中文

中文关键词：癌,肝细胞;超声检查;热消融技术;免疫检查点

外文关键词：carcinoma,hepatocellular;ultrasonography;thermal ablation technique;immune checkpoint

摘要：超声引导下热消融因其微创、并发症少等优点已成为治疗肝细胞癌(HCC)的重要手段之一,不仅疗效确切,而且能够增强抗肿瘤免疫反应;但作为局部治疗手段,复发是影响其疗效的首要问题。近年来,免疫检查点抑制剂的出现,使得免疫联合局部治疗极具探索价值。本文主要针对超声引导下热消融联合免疫检查点抑制剂治疗HCC研究进展进行综述。
Ultrasound-guided thermal ablation has become an important method for treatment of hepatocellular carcinoma(HCC) due to its advantages of minimally invasive and less complications, which not only has curative effect, but also can enhance the anti-tumor immune response of patients. However, as a local treatment, tumor recurrence has become the primary problem affecting curative effect of thermal ablation. In recent years, immunotherapy combined with local therapy has exhibited great exploration value with the emergence of immune checkpoint inhibitors. The advancements of ultrasound-guided thermal ablation combined with immune checkpoint inhibitors in treatment of HCC were mainly reviewed in this article.