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不同产地丹参药材中丹参酮ⅡA和丹酚酸B含量比较     被引量:16

Comparison of the Contents of Tanshinone ⅡA and Salvianolic Acid B in Salviae Miltiorrhizae from Different Producing Areas

文献类型:期刊文献

中文题名:不同产地丹参药材中丹参酮ⅡA和丹酚酸B含量比较

英文题名:Comparison of the Contents of Tanshinone ⅡA and Salvianolic Acid B in Salviae Miltiorrhizae from Different Producing Areas

作者:陈彻[1];王勇[1];王晶[1];李海龙[1];杨雅丽[1];王芳[1];楚惠媛[1]

第一作者:陈彻

机构:[1]甘肃中医学院,甘肃兰州730000

第一机构:甘肃中医药大学

年份:2014

卷号:42

期号:1

起止页码:32

中文期刊名:中医药学报

外文期刊名:Acta Chinese Medicine and Pharmacology

收录:CSTPCD

基金:甘肃省财政厅基本科研业务费专用资金资助(甘财政[2010]176号)

语种:中文

中文关键词:丹参;丹参酮ⅡA;丹酚酸B;高效液相色谱法;产地

外文关键词:Salviae miltiorrhizae; TanshinoneⅡA; Salvianolic acid B; HPLC; Producing area

摘要:目的:测定和比较不同大规模栽培产地丹参药材中丹参酮ⅡA和丹酚酸B含量。方法:采用高效液相色谱法,选用Synchropak PR100-5色谱柱,检测波长分别为270nm和286nm。结果:丹参酮ⅡA和丹酚酸B含量均较高的是四川中江栽培品。山西芮城栽培品丹参酮ⅡA含量尽管最低,但丹酚酸B含量却最高。结论:丹参中丹参酮ⅡA和丹酚酸B的含量与产地关系较大,此研究结果可作为丹参药材采购及临床选用的参考依据。
Objective: To determine and compare the contents of tanshinoneⅡA and salvianolic acid B in salviae miltiorrhizae from different producing areas. Methods: HPLC was employed to determine the contents of tanshinoneⅡA and salvianolic acid B. Synchropak PR100- 5 column was adopted in this process. The detective wavelength was set at 270 nm and 286nm,respectively. Results: Both of tanshinone ⅡA and salvianolic acid B levels of salviae miltiorrhizae from Sichuan Zhongjiang were higher. However,the tanshinone ⅡA level of salviae miltiorrhizae from Shanxi Ruicheng was the lowest,but salvianolic acid B level was the highest. Conclusion: The contents of tanshinoneⅡA and salvianolic acid B in salviae miltiorrhizae could be related to different producing areas. The results can be used as a reference for purchasing and using salviae miltiorrhizae in clinic.

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