详细信息
归芪胶囊对家兔心肌缺血-再灌注损伤血清中谷胱甘肽过氧化物酶、过氧化氢的影响 被引量:2
The Effect of Guiqi Capsule on Serum GSH-PX and H_2O_2 of Rabbit with Myocardial-Ischemia-Reperfusion Injury
文献类型:期刊文献
中文题名:归芪胶囊对家兔心肌缺血-再灌注损伤血清中谷胱甘肽过氧化物酶、过氧化氢的影响
英文题名:The Effect of Guiqi Capsule on Serum GSH-PX and H_2O_2 of Rabbit with Myocardial-Ischemia-Reperfusion Injury
作者:王昕[1]
第一作者:王昕
机构:[1]甘肃中医学院生物化学教研室,甘肃兰州730000
第一机构:甘肃中医药大学基础医学院(敦煌医学研究所)
年份:2005
卷号:12
期号:12
起止页码:26
中文期刊名:中国中医药信息杂志
外文期刊名:Chinese Journal of Information on Traditional Chinese Medicine
收录:CSTPCD;;CSCD:【CSCD_E2011_2012】;
基金:甘肃省科学技术攻关项目(GS022-A43-140)
语种:中文
中文关键词:归芪胶囊;心肌缺血-再灌注损伤;过氧化物酶;过氧化氢
外文关键词:Guiqi capsule compound; GSH-PX;H2O2; myocardial ischemia-reperfusion injury
摘要:目的探讨归芪胶囊对家兔心肌缺血-再灌注损伤的保护作用。方法以家兔血清中谷胱甘肽过氧化物酶(GSH-PX)、过氧化氢(H2O2)为指标进行实验观察。结果归芪胶囊对心肌缺血-再灌注损伤家兔血清中GSH-PX的升高与H2O2的降低有显著作用(P<0.01)。结论归芪胶囊通过对GSH-PX与H2O2含量的影响,对再灌注心肌损伤有保护作用。
Objective To approach the protective actions of Guiqi capsule compound to the rabbits of myocardial ischemia-reperfusion injury. Method To observe the indexes-GSH-PX and H2O2-from the rabbits blood in order to prove effect of the medicine. Result The group medicine used Guiqi capsule compound had an obviously increase the GSH-PX and decrease the H2O2 to myocardial ischemia-reperfusion injury. Conclusion The medicine-Guiqi capsule compound-has obviously protective action to myocardial ischemia-reperfusion injury by the way of regulating the serum content of GSH-PX and H2O2.
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