文献类型：期刊文献

中文题名：正常妊娠与妊娠高血压综合征孕妇D-二聚体水平分析

英文题名：Analysis of D-dimer level of normal pregnancy and pregnancy hypertension syndrome pregnant woman

作者：李明兰[1]

第一作者：李明兰

机构：[1]甘肃中医学院附属医院妇产科(甘肃兰州),730020

第一机构：甘肃中医药大学第二附属医院

年份：2014

卷号：16

期号：25

起止页码：121

中文期刊名：中国社区医师（医学专业）

语种：中文

中文关键词：妊娠;妊娠高血压综合征;D-二聚体

外文关键词：Pregnancy;;Pregnancy induced hypertension syndrome;;D-dimmer

摘要：目的:分析正常妊娠与妊娠高血压综合征孕妇血浆D-二聚体水平差异,探讨高血压对妊娠期妇女D-二聚体水平的影响。方法:2010年3月-2013年10月收治妊娠期孕妇128例,按照是否合并高血压分为妊娠期高血压综合征组(60例)和正常妊娠组(68例),另选择同期健康女性70例作为对照组。对比3组血浆D-二聚体水平。结果:妊娠高血压组、正常妊娠组D-二聚体水平显著高于对照组(P<0.05,P<0.01)。妊娠高血压组D-二聚体水平显著高于正常妊娠组(P<0.05);不同程度妊娠高血压之间血浆D-二聚体水平差异具有统计学意义(P<0.05)。结论:正常妊娠者血浆D-二聚体含量增高,血液趋于高凝状态。妊娠高血压疾病患者伴有凝血系统的病理学改变,其血浆D-二聚体水平较正常妊娠更高。建议对妊娠高血压患者进行严格的血浆D-二聚体水平监测,以及时了解是否存在血栓性病变,有效保护母婴健康。
Objective:To analyze the difference of D-dimer level of normal pregnancy and pregnancy hypertension syndrome pregnant woman,and to explore the influence of hypertension on D-two dimer level of pregnant women.Methods:128 pregnant women were selected from March 2010 to October 2013.According to with hypertension or not,they were divided into the pregnancy induced hypertension syndrome group(60 cases) and the normal pregnancy group(68 cases),at the same time,70 healthy women were selected as the control group.We compared the plasma D-dimer level of the three groups.Results:The D-dimer level of pregnancy induced hypertension group and normal pregnancy group were significantly higher than those of the control group(P0.05,P0.01).The D-dimer level of pregnancy induced hypertension group were significantly higher than that of normal pregnancy group(P0.05);between the different degree pregnancy induced hypertension,the plasma D-dimer level had significant difference(P0.05).Conclusion:The plasma D-dimer content of normal pregnancy is increased,and the blood is become hypercoagulable state.Patients with hypertensive disorders in pregnancy have the pathological changes of the coagulation system,and the plasma D-dimer level is higher than that of normal pregnancy.We suggest that we should examine the plasma D-dimer level of patients with hypertension of pregnancy,and understand the existence of thrombotic diseases,to protect the health of mother and infant.