文献类型：期刊文献

英文题名：Varicose vein in patients under the age of 40: A multicenter case-control study

作者：Tu, Jing[1];Li, Xinwei[2];Huang, Lirui[2];Sun, Jinhong[3];Wang, Xiang[4];Xu, Pengfu[5];Chen, Yulin[6];Zhao, Wenjun[4];Wu, Ziheng[2];Pan, Yun[1,2];Qiu, Chenyang[2]

第一作者：Tu, Jing

通信作者：Pan, Y[1];Qiu, CY[1]

机构：[1]Zhejiang Univ, Affiliated Hosp 1, Sch Med, Dept Nursing, Hangzhou, Peoples R China;[2]Zhejiang Univ, Affiliated Hosp 1, Sch Med, Dept Vasc Surg, 79 Qingchun Rd, Hangzhou 310003, Peoples R China;[3]Zhejiang Univ, Lishui Hosp Zhejiang Prov, Dept Vasc Surg, Lishui, Peoples R China;[4]Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Dept Vasc Surg, Taizhou, Peoples R China;[5]Zhejiang Univ, Taizhou Hosp Zhejiang Prov, Dept Gastrointestinal Surg, Taizhou, Peoples R China;[6]Gansu Univ Chinese Med, Dept Tradit Chinese & Western Med, Lanzhou, Peoples R China

第一机构：Zhejiang Univ, Affiliated Hosp 1, Sch Med, Dept Nursing, Hangzhou, Peoples R China

通信机构：[1]corresponding author), Zhejiang Univ, Affiliated Hosp 1, Sch Med, Dept Vasc Surg, 79 Qingchun Rd, Hangzhou 310003, Peoples R China.

年份：2025

外文期刊名：VASCULAR

收录：;Scopus(收录号：2-s2.0-105004648701);WOS:【SCI-EXPANDED(收录号:WOS:001481165100001)】；

语种：英文

外文关键词：Varicose veins; case-control study; young; family history

摘要：Objective: To assess the risk factors for varicose veins in patients under the age of 40 and the long-term results of surgery. Methods: This multicenter case-control study comprised patients who received great saphenous vein stripping and ambulatory phlebectomy between January 2014 and December 2015 and were followed for at least 5 years. Patients under the age of 40 were assigned to Group 1. Patients in Group 2 were selected in a 3:1 ratio by matching their CEAP classification to those in Group 1. We studied their demographics, risk factors, and follow-up findings. Results: There were 42 patients (mean age 35) in Group 1 and 126 patients (mean age 57) in Group 2. Group 2 patients had a higher prevalence of hypertension (16% vs 2%, p = .022). The proportions of C2, C3, C4, C5, and C6 were 52%, 10%, 24%, 10%, and 5%, respectively. For risk factors, only family history was more prevalent in Group 1 (odds ratio 4.9, 95% confidence interval 2.3-10.4). The course of the disease was shorter in Group 1 (p = .003). During a mean follow-up of 79 months, there were no difference in the recurrences of varicose vein, Venous Clinical Severity Score, or Aberdeen Varicose Vein Questionnaire scores (p > .05), which indicated similar 5-year surgery efficacy between the two groups. Conclusion: Family history was more prevalent and the course of the disease was shorter among young patients with varicose veins. The 5-year prognosis of surgery was satisfactory despite the age of receiving the treatment.