文献类型：期刊文献

英文题名：Complementary and alternative therapies for knee osteoarthritis A protocol for systematic review and network meta-analysis

作者：Yu, Haiyang[1,2];Wang, Haiyan[3,4];Cao, Panju[5];Ma, Tao[1];Zhao, Yongli[2];Xie, Feiyang[1];Yao, Chuanjiang[1];Zhang, Xiaogang[1,2]

第一作者：于海洋

通信作者：Zhang, XG[1]

机构：[1]Gansu Univ Chinese Med, Clin Coll Tradit Chinese Med, Lanzhou, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Dept Orthoped, Affiliated Hosp, Lanzhou, Gansu, Peoples R China;[3]Gansu Univ Chinese Med, Dept Acupuncture & Moxibust, Affiliated Hosp, Lanzhou, Gansu, Peoples R China;[4]Chengdu Univ Tradit Chinese Med, Coll Acupuncture & Tuina, Chengdu, Sichuan, Peoples R China;[5]Baoji Hosp Tradit Chinese Med, Dept Spine, Baoji, Shanxi, Peoples R China

第一机构：甘肃中医药大学中医临床学院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Dept Orthoped, Affiliated Hosp, Lanzhou, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2020

卷号：99

期号：44

起止页码：E23035

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85094933765);WOS:【SCI-EXPANDED(收录号:WOS:000588186500097)】；

基金：This study was supported by the National scientific research project of traditional Chinese medicine of China (No. 201507001).

语种：英文

外文关键词：complementary and alternative therapies; knee osteoarthritis; protocol; systematic review

摘要：Background: Knee osteoarthritis (KOA) is a degenerative disease, making a unique contribution to chronic pain, edema, and limited mobility of knee joint. This disease is an important factor affecting the quality of life of middle-aged and elderly people. Complementary and alternative medicine (CAM) therapies have been used clinically to treat KOA; however, the selection strategies of different CAM interventions in clinical practice are still uncertain, and the purpose of this study is to evaluate the efficacy and acceptability of different CAM therapies using systematic review and network meta-analysis. Methods: According to the strategy, the authors will retrieve a total of 7 electronic databases by October 2020, including PubMed, the Cochrane Library, EMbase, China National Knowledge Infrastructure, China Biological Medicine, Chongqing VIP, and Wan-fang databases After a series of screening, 2 researchers will use Aggregate Data Drug Information System and Stata software to analyze the data extracted from the randomized controlled trials of CAM therapies for the KOA. Finally, the evidence grade of the results will be evaluated. Results: This study will provide a reliable evidence for the selection of CAM therapies for KOA. Conclusion: The results of this study will provide references for evaluating the influence of different CAM therapies for KOA, and provide decision-making references for clinical research. Ethics and dissemination: This study does not require ethical approval. The results will be disseminated through a peer-reviewed publication. OSF registration number: DOI 10.17605/OSF.IO/GJMF4.