详细信息
基于脑肠轴探讨辛开苦降法对阿尔茨海默病的作用 被引量:4
Exploration on the Effect of Pungent Dispersing and Bitter Descending Method on Alzheimer’s Disease Based on Brain-Gut Axis
文献类型:期刊文献
中文题名:基于脑肠轴探讨辛开苦降法对阿尔茨海默病的作用
英文题名:Exploration on the Effect of Pungent Dispersing and Bitter Descending Method on Alzheimer’s Disease Based on Brain-Gut Axis
作者:王帅哲[1];王佳伟[1];魏本君[1,2,3]
第一作者:王帅哲
机构:[1]甘肃中医药大学,甘肃兰州730000;[2]敦煌医学与转化教育部重点实验室,甘肃兰州730000;[3]甘肃省中医方药挖掘与创新转化重点实验室,甘肃兰州730000
第一机构:甘肃中医药大学
年份:2023
卷号:51
期号:12
起止页码:10
中文期刊名:中医药学报
外文期刊名:Acta Chinese Medicine and Pharmacology
收录:CSTPCD
基金:甘肃省自然科学基金(20JR5RA180);甘肃中医药大学引进人才项目(2018YJRC-06);甘肃中医药大学甘肃省中医方药挖掘与创新转化重点实验室开放基金(zyzx-2020-11);敦煌医学与转化教育部重点实验室开放基金(DHYX17-02)。
语种:中文
中文关键词:阿尔茨海默病;肠道菌群;脑肠轴;辛开苦降法
外文关键词:Alzheimer's disease;Intestinal flora;Brain-gut axis;Pungent dispersing and bitter descending method
摘要:阿尔茨海默病(AD)是一种常见的年龄依赖性神经退行性疾病。中医学认为,肠道菌群和脑肠轴类似于脾胃及脑与脾胃间的关系。对于脾胃气机不畅的问题,辛开苦降法是一种行之有效的疗法。本文以分析肠道菌群、脑肠轴和AD之间的联系为基础,提出运用辛开苦降法来治疗AD的新思路,旨在为临床AD治疗带来新的观点和方法。
Alzheimer's disease(AD)is a common age-dependent neurodegenerative disease.Traditional Chinese medicine(TCM)believes that the relationship between gut flora and brain-gut axis is similar to the relationship between the spleen-stomach and the brain-spleen-stomach.Pungent dispersing and bitter descending method is an effective treatment method for inhibited spleen-stomach qi movement.Based on the analysis of the relationship between intestinal microflora,brain-gut axis and AD,the authors put forward pungent dispersing and bitter descending method for the treatment of AD,hoping to provide new idea and method for clinical treatment for AD.
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