文献类型：期刊文献

英文题名：Meta-analysis of right ventricular function in patients with aortic stenosis after transfemoral aortic valve replacement or surgical aortic valve replacement

作者：Cao, Yunshan[1,2];Singh, Vikas[6];Wang, Aqian[1];Zhang, Liyan[7];He, Tingting[7];Su, Hongling[1];Wei, Rong[1];Duan, Yichao[8];Jiang, Kaiyu[7];Wu, Wenyu[8];Huang, Yan[1];Elmariah, Sammy[9];Qi, Guanming[10];Su, Xin[7];Zhang, Yan[4,5];Zhang, Min[3]

第一作者：Cao, Yunshan

通信作者：Cao, YS[1];Cao, YS[2]

机构：[1]Gansu Prov Hosp, Dept Cardiol, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China;[2]Shanxi Med Univ, Dept Cardiol, Shanxi Cardiovasc Hosp, Taiyuan, Peoples R China;[3]Gansu Prov Hosp, Dept Pathol, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China;[4]Tianjin Med Univ, Eye Hosp, Dev Ctr Ophthalmol & Vis Sci, Eye Inst, 251 Fukang Rd, Tianjin, Peoples R China;[5]Tianjin Med Univ, Eye Hosp, Sch Optometry, 251 Fukang Rd, Tianjin, Peoples R China;[6]Univ Louisville, Sch Med, Div Cardiovasc Med, Louisville, KY 40292 USA;[7]Gansu Univ Chinese Med, Clin Med Sch, Lanzhou, Peoples R China;[8]Ningxia Med Univ, Sch Clin Med, Yinchuan, Ningxia, Peoples R China;[9]Harvard Med Sch, Massachusetts Gen Hosp, Dept Med, Cardiol Div, Boston, MA 02115 USA;[10]Tufts Med Ctr, Pulm & Crit Care Div, Boston, MA 02111 USA

第一机构：Gansu Prov Hosp, Dept Cardiol, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Cardiol, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China;[2]corresponding author), Shanxi Med Univ, Dept Cardiol, Shanxi Cardiovasc Hosp, Taiyuan, Peoples R China.

年份：2020

卷号：11

外文期刊名：THERAPEUTIC ADVANCES IN CHRONIC DISEASE

收录：;Scopus(收录号：2-s2.0-85087394356);WOS:【SCI-EXPANDED(收录号:WOS:000549102900001)】；

基金：The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the National Natural Science Foundation of China (81770300, 81860059, 81460072); CAS "Light of West China" Program; International Joint Research Program of Gansu Province (18YF1WA046); Innovation and Entrepreneurship Program of Lanzhou City (2018-RC-78); the Science Foundation of Gansu Provincial Hospital (18GSSY5-4)

语种：英文

外文关键词：aortic valve stenosis; AS; right ventricule; right ventricular function; SAVR; surgical aortic valve replacement; TAVI; TAVR; TF-TAVR; transcatheter aortic valve implantation; transcatheter aortic valve replacement; transfemoral-aortic valve replacement

摘要：Background: Right ventricular function (RVF) is an independent predictor of prognosis for patients undergoing aortic valve replacement: transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR). The effect of transfemoral aortic valve replacement (TF-TAVR) on RVF is uncertain. We aimed to perform a meta-analysis of the effect of TF-TAVR on RVF in patients with aortic stenosis (AS) and compare the effect of TF-TAVR with SAVR. Methods: We searched relevant studies from PubMed, Embase, Cochrane Library databases, and Web of Science. Furthermore, two reviewers (Wang AQ and Cao YS) extracted all relevant data, which were then double checked by another two reviewers (Zhang M and Qi GM). We used the forest plot to present results. Tricuspid annular plane systolic excursion (TAPSE) was the primary outcome. Results: This meta-analysis included 11 studies. There were 353 patients who underwent TF-TAVR, and 358 patients who were subjected to SAVR. There was no significant difference in TAPSE at 1 week and 6 months as well as right ventricular ejection fraction (RVEF) at <2 weeks and 6 months after TF-TAVR. For the SAVR group, TAPSE at 1 week and 3 months as well as fractional area change (FAC) at 3 months post procedure were significantly aggravated, while RVEF did not change significantly. Moreover, TAPSE post-TF-TAVR was significantly improved as compared with post-SAVR. The Delta TAPSE, the difference between TAPSE post-procedure and TAPSE prior to procedure, was also significantly better in the TF-TAVR group than in the SAVR group. Conclusion: RVF was maintained post TF-TAVR. For SAVR, discrepancy in the measured parameters exists, as reduced TAPSE indicates compromised longitudinal RVF, while insignificant changes in RVEF implicate maintained RVF post procedure. Collectively, our study suggests that the baseline RV dysfunction and the effect of TF-TAVR versus SAVR on longitudinal RVF may influence the selection of aortic valve intervention.