文献类型：期刊文献

英文题名：Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS

作者：Du, Bang[1];Liang, Shuxin[2];Zhang, Rui[1];Shi, Wenjia[1];Wang, Ruonan[1];Qin, Yahong[1];Chu, Aiai[1]

第一作者：杜兵

通信作者：Chu, AA[1]

机构：[1]Gansu Univ Chinese Med, Gansu Prov Hosp, Clin Med Sch 1, Dept Echocardiog, Lanzhou, Peoples R China;[2]Shenzhen Ruipuxun Acad Stem Cell & Regenerat Med, Shenzhen, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Gansu Prov Hosp, Clin Med Sch 1, Dept Echocardiog, Lanzhou, Peoples R China.|[10735]甘肃中医药大学;

年份：2025

卷号：42

期号：3

外文期刊名：ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES

收录：;Scopus(收录号：2-s2.0-105000336335);WOS:【SCI-EXPANDED(收录号:WOS:001445610000001)】；

基金：This research was funded by Shenzhen Science and Technology Program (JCYJ20210324122410028), Open Project of State Key Laboratory of Respiratory Disease (SKLRD-OP-202403/202301), and In-Hospital Cultivation Fund of Gansu Provincial Hospital (19SYPYB-2).

语种：英文

外文关键词：echocardiography; exercise capacity; obstructive sleep apnea syndrome; right atrial function; right ventricular function

摘要：Background: Right ventricular (RV) diastolic function and right atrial (RA) function are poorly characterized in patients with obstructive sleep apnea syndrome (OSAS), but may influence exercise capacity. We aimed to evaluate RA function and RV diastolic function in OSAS and study their relationship with exercise capacity. Methods: Fifty-three patients with OSAS and thirty age- and gender-matched controls prospectively underwent echocardiography and cardiopulmonary exercise testing to investigate RV diastolic function, RA function, and exercise capacity. Results: Altered RV diastolic function in patients with severe OSAS was indicated by the increased tricuspid valve E/e ' ratio (TV E/e '), isovolumic relaxation time (IVRT), and by the reduced RV TDI e ' velocity. The TV E/e ' correlated modestly with peak VO2 (r = -0.334, p < 0.01). Patients with severe OSAS exhibited impaired RA total emptying fraction, RA passive emptying fraction, and RA reservoir strain (RARS), with RARS being associated with peak oxygen uptake (VO2) (r = 0.451, p < 0.01 for reservoir function). Conclusion: Altered RA function and RV diastolic function in patients with OSAS are associated with impaired exercise capacity. The correlation of RA function and RV diastolic function with exercise capacity suggests that it may be important to evaluate RA function and RV diastolic function in this population.