文献类型：期刊文献

英文题名：A novel highly sensitive dual-channel chemical sensor for sequential recognition of Cu²⁺ and CN^- in aqueous media and its bioimaging applications in living cells

作者：Xie, Yong-Qiang[1,3];Zhang, You-Ming[1,2];Li, Zhao-Hui[1];Qi, Xiao-Ni[1];Yao, Hong[1];Shi, Bing-Bing[1];Qu, Wen-Juan[1];Wei, Tai-Bao[1];Lin, Qi[1]

第一作者：谢永强;Xie, Yong-Qiang

通信作者：Zhang, YM[1];Wei, TB[1];Lin, Q[1];Zhang, YM[2]

机构：[1]Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Ecoenvironm Related Polymer Mat, Key Lab Polymer Mat Gansu Prov,Minist Educ China, Lanzhou 730070, Gansu, Peoples R China;[2]Gansu Nat Energy Res Inst, Lanzhou 730046, Peoples R China;[3]Gansu Univ Chinese Med, Expt & Training Teaching Ctr, Lanzhou 730000, Gansu, Peoples R China

第一机构：Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Ecoenvironm Related Polymer Mat, Key Lab Polymer Mat Gansu Prov,Minist Educ China, Lanzhou 730070, Gansu, Peoples R China

通信机构：[1]corresponding author), Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Ecoenvironm Related Polymer Mat, Key Lab Polymer Mat Gansu Prov,Minist Educ China, Lanzhou 730070, Gansu, Peoples R China;[2]corresponding author), Gansu Nat Energy Res Inst, Lanzhou 730046, Peoples R China.

年份：2021

卷号：45

期号：39

起止页码：18421

外文期刊名：NEW JOURNAL OF CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000697793500001)】；

基金：This work was supported by the National Natural Science Foundation of China (21661028, 21662031 and 21574104).

语种：英文

摘要：A simple and unique dual-channel chemical probe (DH) was designed and synthesized, which not only realized sequential recognition of Cu2+ and CN- by colorimetric and fluorometric methods, but also realized fluorescence detection of CN-. When different cations (Co2+, Mg2+, Ni2+, Cd2+, Hg2+, Al3+, Ag+, Cu2+, Pb2+, Fe3+, Zn2+ and Ca2+) were added into the solution containing the probe molecule DH, only Cu2+ induced an observable change in the UV-vis and fluorescence spectra, indicating that the probe molecule can be applied for specific recognition of Cu2+. The anti-interference experiment of DH to Cu2+ showed that DH has good selectivity for detecting Cu2+, with a detection limit of 7.05 x 10(-7) M. In particular, the fluorescence "ON-OFF-ON" process can be recycled by sequentially adding Cu2+ and EDTA, and the fluorescence intensity remained unchanged after ten times. This observation suggested that DH can achieve reversible highly sensitive response to Cu2+ and EDTA, and can be used as a hypersensitive logic gate for Cu2+ detection. More interestingly, when different anions (CH3COO-, SO32-, H2PO(4)(-), ClO4-, NO3-, HSO4-, I-, Cl-, F-, Br-, N-3(-) and CN-) were added into the solution containing DH and Cu2+, only CN- induced color change of the solution from red to yellowish green, and the fluorescence intensity greatly enhanced, indicating that DH-Cu2+ has a specific response to CN-. The anti-interference experiment showed that DH-Cu2+ has good selectivity for CN-, with a detection limit of 8.11 x 10(-6) M. Moreover, the probe molecule DH can detect CN-, with a detection limit of 7.61 x 10(-6) M. Experimental and theoretical methods were applied to deeply study the detection mechanism of DH, present great potential in practical application for ion test strips and HeLa cell imaging reagents.