文献类型：期刊文献

中文题名：常规治疗联合补肾滋阴、益气养血法治疗失眠的Meta分析

英文题名：Meta-analysis of Tonifying Kidney,Nourishing yin,Nourishing Qi and Nourishing Blood and Traditional Chinese Medicine Combined with Conventional Treatment for Insomnia

作者：王新强[1];冯明霞[2];赵信科[1,2];卢玉俊[2];蒋虎刚[1,2];汪鸣[1];李应东[1,2]

第一作者：王新强

机构：[1]甘肃中医药大学,兰州730000;[2]甘肃中医药大学附属医院,兰州730020

第一机构：甘肃中医药大学

年份：2021

卷号：8

期号：3

起止页码：405

中文期刊名：世界睡眠医学杂志

外文期刊名：World Journal of Sleep Medicine

基金：中医药循证能力建设项目(2019XZZX-XXG002);国家重点研发计划资助项目(2018YFC1705604);2018中医药防治重大疾病科研课题项目(GZKZD-2018-02);国家自然科学基金项目(81860786)。

语种：中文

中文关键词：补肾滋阴;益气养血法;失眠;Meta分析

外文关键词：Invigorating the kidney and nourishing yin,replenishing qi and nourishing blood;Insomnia;Meta analysis

摘要：目的:基于Meta分析系统评价常规治疗联合补肾滋阴、益气养血法治疗失眠的临床疗效。方法:采用计算机检索和手动检索相结合的检索策略,检索中国知网、万方、维普、Pubmed、Cochrane Library等数据库有关补肾、滋阴、益气、养血治疗失眠的临床研究,手动检索《世界睡眠医学杂志》的失眠临床研究,并对纳入的临床研究依次进行文献质量评价,后采用RevMan 5.3对纳入研究的匹兹堡睡眠质量指数、中医症候积分、睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物应用情况、总有效率等指标进行Meta分析。结果:本研究共纳入12篇临床研究,文献质量评价发现上述12篇研究中无低质量文献;Meta分析显示,在常规治疗的基础上联合补肾滋阴、益气养血中药复方、制剂,可显著改善失眠患者的总有效率、匹兹堡睡眠质量指数、中医症候积分、睡眠质量、入睡时间、睡眠时间、睡眠效率、日间功能障碍、睡眠障碍、催眠药物应用情况等指标。结论:常规治疗联合补肾滋阴、益气养血法中药汤剂、复方制剂可明显提高失眠的临床疗效。
Objective:To evaluate the clinical efficacy of conventional treatment combined with kidney tonifying yin and tonifying qi and nourishing blood on insomnia based on the meta-analysis system.Methods:Using a combination of computer and manual search,we searched the clinical research in CNKI,Wanfang,Weipu,Pubmed,Cochrane Library databases about invigorating the kidney,nourishing yin,nourishing qi,and nourishing blood for insomnia.Manually retrieved the clinical study of insomnia in the“World Journal of Sleep Medicine”,and all of the literatures were accepted the quality evaluation by Improved Jadad Quality Evaluation Form,and then adopted RevMan 5.3 for the indicators of Pittsburgh Sleep Quality Index,TCM Symptom Score,Sleep Quality,Sleep Time,Sleep time,sleep efficiency,sleep disturbance,hypnotic drug application,total effective rate and those indicators were meta-analyzed.Results:A total of 12 clinical studies were included in this study,and no low-quality literature was found in the above 12 studies.Meta analysis showed that in combination with conventional treatment,kidney and kidney yin,Yiqiyangxue traditional Chinese medicine prescriptions and preparations can be used to significantly improve the indicators of total effective rate of patients with insomnia,Pittsburgh sleep quality index,TCM syndrome score,sleep quality,sleep time,sleep time,sleep efficiency,daytime dysfunction,sleep disorder,hypnotic drug application.Conclusion:Conventional treatment combined with traditional Chinese medicine prescriptions and preparations for invigorating the kidney and nourishing yin,nourishing qi and nourishing blood can obviously improve the clinical efficacy of insomnia.