文献类型：期刊文献

英文题名：Efficacy and safety of percutaneous endoscopic decompression via transforaminal and interlaminar approaches for lumbar spine stenosis Protocol for a systematic review and meta-analysis

作者：Li, Yuan Zhen[1];Zhang, Hong Wei[1,2];Zhang, Xiao Gang[1];Zhang, Hui[3];Pan, Li[4];Zhao, Xi Yun[1];Ning, Xue Qian[1];Wang, Zhi Peng[1]

第一作者：李元贞

通信作者：Wang, ZP[1]

机构：[1]Gansu Univ Tradit Chinese Med, Dept Orthoped, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730000, Peoples R China;[2]Gansu Univ Tradit Chinese Med, Clin Coll Chinese Med, Lanzhou, Peoples R China;[3]Gansu Prov Peoples Hosp, Dept Orthoped, Lanzhou, Peoples R China;[4]Gansu Univ Tradit Chinese Med, Affiliated Hosp, Lanzhou, Peoples R China

第一机构：甘肃中医药大学第二附属医院

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Dept Orthoped, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730000, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2020

卷号：99

期号：1

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85077458723);WOS:【SCI-EXPANDED(收录号:WOS:000525863600034)】；

基金：This work was supported by Gansu administration of traditional Chinese medicine project grant number GZK-2017-17 and National natural science foundation of China grant number 81560780.

语种：英文

外文关键词：interlaminar; lumbar spinal stenosis; percutaneous endoscopic decompression; systematic review; transforaminal

摘要：Background: Lumbar spinal stenosis (LSS) is a common and frequently-occurring disease in the elderly. Percutaneous endoscopic decompression (PED) has become the first choice for the treatment of LSS because of its small wound, mild pain and rapid recovery. The surgical approaches are mainly divided into percutaneous interlaminar approach and transforaminal approach. However, these two surgical approaches have their own advantages, disadvantages and indications. Hence, the present study aims to synthesize the available direct and indirect evidence of transforaminal approach and interlaminar approach to prove their respective advantages and disadvantages. Methods: The following databases will be searched: Cochrane Library, PubMed, Web of Science, Embase, CNKI, Wanfang data, and China Biomedical Literature Database (CBM). The search dates will be set from the inception to November 2019. Two researchers independently screened the literature, extracted the data and assessed the risk of bias in the included studies. The efficacy outcomes including: Back and Leg Visual Analog Scale (VAS) score, the MacNab criteria, the Oswestry Disability Index (ODI) and Japanese Orthopedic Association (JOA) score. The safety outcomes including: incidence of complications (dura tear, incomplete decompression, reoperation, etc.). The meta-analysis will be conducted using Stata 12.0 software. Grading of Recommendations Assessment, Development and Evaluation (GRADE) will be used to assess evidence quality. Results: The results of this meta-analysis will be published in a peer-reviewed journal. Conclusion: The meta-analysis will provide a comprehensive summary of the evidence for 2 approaches to PED in patients with LSS. Protocol registration number: CRD42019128080.