文献类型：期刊文献

英文题名：TCM nonpharmacological interventions for chronic low-back pain A protocol for systematic review and network meta-analysis

作者：Yu, Haiyang[1,2];Wang, Haiyan[3,4];Ma, Tao[1];Huang, Ailing[4];Lu, Zengpeng[1,2];Zhang, Xiaogang[1,2]

第一作者：于海洋

通信作者：Zhang, XG[1]

机构：[1]Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Affiliated Hosp, Dept Orthoped, Lanzhou, Gansu, Peoples R China;[3]Gansu Univ Chinese Med, Affiliated Hosp, Dept Acupuncture & Moxibust, Lanzhou, Gansu, Peoples R China;[4]Chengdu Univ Tradit Chinese Med, Coll Acupuncture & Tuina, Chengdu, Sichuan, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Affiliated Hosp, Dept Orthoped, Lanzhou, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2020

卷号：99

期号：40

起止页码：E22547

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85092647825);WOS:【SCI-EXPANDED(收录号:WOS:000579119300087)】；

基金：This study was supported by the National scientific research project of traditional Chinese medicine of China (No.201507001).

语种：英文

外文关键词：chronic low back pain; protocol; systematic review; TCM nonpharmacological interventions

摘要：Background: chronic low back pain (CLBP) are common symptoms bothering people in daily life. Traditional Chinese medicine (TCM) nonpharmacological interventions are gaining an increasing popularity for CLBP. Nevertheless, the evidence of efficacy and safety of random controlled trials (RCTs) remains controversial. This study aims to evaluate the efficacy and acceptability of different TCM nonpharmacological therapies by systematic review and network meta-analysis. Methods: According to the strategy, The authors will retrieve a total of 7 electronic databases by September 2020, including PubMed, the Cochrane Library, EMbase, China National Knowledge Infrastructure, China Biological Medicine, Chongqing VIP, and Wan-fang databases After a series of screening, 2 researchers will use Aggregate Data Drug Information System and Stata software to analyze the data extracted from the randomized controlled trials of TCM nonpharmacological interventions for CLBP. The primary outcome will be the improvement of Pain intensity and functional status/disability and the secondary outcomes will include lobal improvement, health-related quality of life, satisfaction with treatment, and adverse events. Both classical meta-analysis and network meta-analysis will be implemented to investigate direct and indirect evidences on this topic. The quality of the evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation instrument. Results: This study will provide a reliable evidence for the selection of TCM nonpharmacological therapies in the treatment of CLBP. Conclusion: This study will generate evidence for different TCM nonpharmacological therapies for CLBP and provide a decision-making reference for clinical research. Ethics and dissemination: This study does not require ethical approval. The results will be disseminated through a peer-reviewed publication. OSF registration number: DOI 10.17605/OSF.IO/4H3Y9.