文献类型：期刊文献

英文题名：Ultrasensitive Detection of Ferulic Acid Using Poly(diallyldimethylammonium chloride) Functionalized Graphene-Based Electrochemical Sensor

作者：Liu, Lin-jie[1];Gao, Xia[1];Zhang, Pei[1];Feng, Shi-lan[1];Hu, Fang-di[1];Li, Ying-dong[2];Wang, Chun-ming[3]

第一作者：Liu, Lin-jie

通信作者：Hu, FD[1]

机构：[1]Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China;[2]Gansu Coll Tradit Chinese Med, Lanzhou 730000, Peoples R China;[3]Lanzhou Univ, Dept Chem, Lanzhou 730000, Peoples R China

第一机构：Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.

年份：2014

卷号：2014

外文期刊名：JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY

收录：;Scopus(收录号：2-s2.0-84901794477);WOS:【SCI-EXPANDED(收录号:WOS:000336310500001)】；

基金：This work is greatly supported by the "Twelfth Five-Year" National Science and Technology Support Program of China (no. 2011BAI05B02).

语种：英文

摘要：The electrochemical redox of ferulic acid (FA) was investigated systematically by cyclic voltammetry (CV) with a poly(diallyldimethylammoniumchloride) functionalized graphene-modified glassy carbon electrode (PDDA-G/GCE) as a working electrode. A simple and sensitive differential pulse voltammetry (DPV) technique was proposed for the direct quantitative determination of FA in Angelica sinensis and spiked human urine samples for the first time. The dependence of the intensities of currents and potentials on nature of the supporting electrolyte, pH, scan rate, and concentration was investigated. Under optimal conditions, the proposed sensor exhibited excellent electrochemical sensitivity to FA, and the oxidation peak current was proportional to FA concentration in the range of 8.95 X 10(-8) M similar to 5.29 X 10(-5) M, with a relatively low detection limit of 4.42 X 10(-8) M. This fabricated sensor also displayed acceptable reproducibility, long-term stability, and high selectivity with negligible interferences from common interfering species. Besides, it was applied to detect FA in Angelica sinensis and biological samples with satisfactory results, making it a potential alternative tool for the quantitative detection of FA in pharmaceutical analysis.