文献类型：期刊文献

英文题名：Lung abscess secondary to lung cancer with a coinfection of Granulicatellaadiacens and other bacteria: a case report

作者：Yang, Shuo[1];Wu, Liangliang[1];Xu, Lili[2];Huang, Xiang[1];Sun, Xiaofeng[3];Yang, Lan[1];Xu, Ling[1]

第一作者：Yang, Shuo

通信作者：Sun, XF[1]

机构：[1]Xinjiang Med Univ, Clin Coll 1, Urumqi City, Peoples R China;[2]Gansu Univ tradit Chinese Med, Lanzhou, Gansu, Peoples R China;[3]Xinjiang Med Univ, Infect Ctr, Affiliated Hosp 1, Urumqi City, Peoples R China

第一机构：Xinjiang Med Univ, Clin Coll 1, Urumqi City, Peoples R China

通信机构：[1]corresponding author), Xinjiang Med Univ, Infect Ctr, Affiliated Hosp 1, Urumqi City, Peoples R China.

年份：2021

卷号：21

期号：1

外文期刊名：BMC INFECTIOUS DISEASES

收录：;Scopus(收录号：2-s2.0-85109735222);WOS:【SCI-EXPANDED(收录号:WOS:000672664300005)】；

基金：Thanks to the Dr. Xiaofeng Sun for professional explaination of the bacteria.

语种：英文

外文关键词：Granulicatella adiacens; Eikenella corrodens; Lung abscess; Lung cancer; Case report

摘要：Background Granulicatella adiacens is facultative anaerobic Gram-positive bacteria, which mainly involve bacterial endocarditis and bacteremia, but there are few reports of local suppurative infection. A case of lung abscess with a coinfection of Granulicatella adiacens and other bacteria in a lung cancer patient will be reported in this paper. To our knowledge, this is the first case report describing lung abscess due to G.adiacens. Case presentation A 52-year-old Chinese woman was admitted to the hospital, She complained of coughing and expectoration for 1 month, shortness of breath for half a month, and dyspnea for 1 day. After a series of examinations, she was diagnosed with lung abscess, pleural effusion, and bronchogenic carcinoma. Draining pus culture demonstrated Granulicatella adiacens. After more than 5 weeks of antibiotic therapies in total, she gradually recovered to fight against lung cancer. Conclusion This is the first reported lung abscess caused by G.adiacens. In immunosuppressed hosts, G.adiacens is a virulent pathogen associated with a spectrum of intrathoracic suppurative. Earlier diagnosis and proper drainage surgery with effective antibiotics treatment are very important, and antimicrobial treatment should be more than 5 weeks. When complex pulmonary infection interferes with the CT diagnosis, clinical suspicion of lung cancer should be increased if G.adiacens or Eikenella corrodens is detected from a pulmonary infection.