文献类型：期刊文献

英文题名：Plant-Microbiome Interactions in Medicinal Plants: A Synergistic Partnership for Biomass Production and Secondary Metabolite Accumulation

作者：Wang, Erjun[1];Zhang, Yalong[1];Yue, Ronghua[1];Wang, Yuanyuan[1];Ma, Xiaohui[1];Zhang, Gaosen[1,2];Jin, Ling[1]

第一作者：Wang, Erjun

通信作者：Zhang, GS[1];Jin, L[1];Zhang, GS[2]

机构：[1]Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730000, Peoples R China;[2]Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730000, Peoples R China;[2]corresponding author), Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, Lanzhou 730000, Peoples R China.|[1073501e14fb35863569f]甘肃中医药大学药学院（西北中藏药协同创新中心办公室）;[10735]甘肃中医药大学;

年份：2026

卷号：14

期号：8

外文期刊名：MICROORGANISMS

收录：;Scopus(收录号：2-s2.0-105048316911);WOS:【SCI-EXPANDED(收录号:WOS:001859540300001)】；

基金：This work is supported by the Earmarked fund for Gansu Agriculture Research System (GSRAS-06), National Modern Agricultural Industrial Technology System Project of the Ministry of CARS-Finance and the Ministry of Agriculture and Rural Affairs (CARS-21), Gansu Provincial Higher Education Faculty Innovation Fund Project (2025A-116), Gansu Provincial Joint Research Fund Major Project: Study on the Variation Pattern sand Key Control Technologies of Angelica sinensis Early Bolting Affected by Extreme Weather (25JRRA1171), Northwest China-Tibet Medicine Collaborative Innovation Center (2026), and Supported by the Science and Technology Program of Lanzhou City (2025KJZC00005).

语种：英文

外文关键词：medicinal plants; plant microbiome; SynComs; secondary metabolites; co-evolution

摘要：Medicinal plants are important sources of secondary metabolites (SMs), but their production is constrained by resource shortages, low cultivation efficiency, and continuous cropping obstacles. As the "second genome" of host plants, the plant microbiome is deeply involved in plant growth and development, stress adaptation, and the accumulation of bioactive compounds, providing new pathways for the sustainable utilization of traditional Chinese medicine resources. This review summarizes the mechanisms by which the plant microbiome regulates biomass formation and SM accumulation in medicinal plants. Microorganisms can promote plant nutrient acquisition, enhance resistance to biotic and abiotic stresses, and regulate root architecture and hormonal signaling. Meanwhile, microorganisms can also participate in the remodeling of secondary metabolic networks in medicinal plants through elicitor- and effector protein-mediated signal transduction, regulation of metabolic gene expression, redistribution of photosynthetic carbon sources and metabolic precursors, and their own biosynthetic capacities. From the perspective of co-evolution, plants and their microbiomes constitute symbiotic systems formed through long-term interactions. Plants can selectively recruit specific microbial taxa through root exudates, SMs, and signaling molecules, whereas microorganisms influence plant adaptability and medicinal material quality through colonization, metabolic feedback, and horizontal gene transfer. This review proposes that a synergistic regulatory pattern of "close phylogenetic relatedness-similar secretions-similar microbial communities" may exist between medicinal plants and microorganisms. This pattern suggests that closely related medicinal plants may share similar core microbial taxa, which may help reveal the intrinsic mechanisms underlying specific microbial recruitment and the quality formation of geo-authentic medicinal materials. Furthermore, the design of synthetic microbial communities (SynComs) can be achieved based on the identification of shared functional genes and the screening of indigenous core functional strains.