文献类型：期刊文献

英文题名：Advances in the use of structural and diffusion magnetic resonance imaging for characterizing SCD and MCI due to Alzheimer's disease

作者：Yang, Hao[1,2];Dong, Cheng[1,3];Cai, Ying[1,2];Zhao, Mingming[1,2];Liu, Junfang[1,2];Bian, Shizhu[4];Ding, Xiaohan[1,2]

第一作者：Yang, Hao;杨海;杨宏;杨红;杨虹;杨焕

通信作者：Ding, XH[1];Ding, XH[2];Bian, SZ[3]

机构：[1]Chinese Peoples Liberat Army, Joint Logist Support Force, Hosp 940, Lanzhou, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou, Gansu, Peoples R China;[3]Northwest Minzu Univ, Sch Med, Lanzhou, Gansu, Peoples R China;[4]Army Mil Med Univ, Affiliated Hosp 2, Chongqing, Peoples R China

第一机构：Chinese Peoples Liberat Army, Joint Logist Support Force, Hosp 940, Lanzhou, Gansu, Peoples R China

通信机构：[1]corresponding author), Chinese Peoples Liberat Army, Joint Logist Support Force, Hosp 940, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou, Gansu, Peoples R China;[3]corresponding author), Army Mil Med Univ, Affiliated Hosp 2, Chongqing, Peoples R China.|[10735]甘肃中医药大学;

年份：2025

卷号：19

外文期刊名：FRONTIERS IN NEUROSCIENCE

收录：;Scopus(收录号：2-s2.0-105015087509);WOS:【SCI-EXPANDED(收录号:WOS:001564309900001)】；

语种：英文

外文关键词：subjective cognitive decline; mild cognitive impairment; structural magnetic resonance imaging; sMRI; diffusion tensor imaging; DTI

摘要：Alzheimer's disease (AD) has become a great concern for society in general and clinicians specifically because of its high morbidity, relative lack of awareness of its characteristics, and low diagnosis and treatment rates. Worldwide, there is a lack of effective treatments for slowing the progression of AD in clinical practice. Thus, the management of patients in the preclinical phase of AD (PPAD) has been identified to be highly important for addressing this concern. PPAD is considered a preclinical manifestation of the early stages of AD and includes subjective cognitive decline (SCD) and mild cognitive impairment (MCI). Developments in magnetic resonance imaging (MRI) technology have led to its demonstration of great potential in the early identification and progression monitoring of PPAD. Thus, in this review, we summarized the concepts, principles and applications of structural and diffusion MRI in the identification of PPAD to provide potential imaging markers that can be used by clinicians in clinical practice.