文献类型：期刊文献

中文题名：放疗在弥漫型胃癌综合治疗中的应用研究进展

英文题名：Research progression in the application of radiotherapy in the comprehensive treatment of diffuse gastric cancer

作者：陈刚[1,2];张敏敏[3];朱军民[1];李玉民[1,2]

第一作者：陈刚

机构：[1]兰州大学第二医院普外科,730030;[2]甘肃省消化系肿瘤重点实验室,兰州730030;[3]甘肃中医药大学内科教研室,兰州730000

第一机构：兰州大学第二医院普外科,730030

年份：2021

卷号：48

期号：2

起止页码：123

中文期刊名：国际外科学杂志

外文期刊名：International Journal of Surgery

收录：CSTPCD

基金：国家自然科学基金委资助项目(31770537);甘肃省卫生行业科研计划项目(GSWSKY-2019-32);甘肃中医药大学中青年科研基金项目(ZQ2017-6)。

语种：中文

中文关键词：放射疗法;综合疗法;外科手术;弥漫型胃肿瘤

外文关键词：Radiotherapy;Combined modality therapy;Surgical procedures,operative;Diffuse gastric tumor

摘要：弥漫型胃癌发病率呈逐年增高趋势,以手术治疗为主的综合治疗是目前的主要方式,恶性程度高,手术切除率低,手术治疗失败的主要原因是局部复发,预后极差。放疗是弥漫型胃癌综合治疗的重要组成部分,术前可降低肿瘤分期,术后可防止复发转移,有效的新辅助放疗是提高弥漫型胃癌患者手术切除率的途径之一。本文综述了弥漫型胃癌的放疗临床应用进展,包括选择合理的放疗体系、精确定位、设定剂量、增敏技术的运用以及增敏的机制此外,介绍了新辅助放疗以及放疗并发症的防治。
The incidence of diffuse gastric cancer is increasing year by year,comprehensive therapy is the main treatment.The main reason of surgical treatment failure is local recurrence,and the long-term curative effect is generally poor.Radiotherapy is an important part of comprehensive treatment for diffuse gastric cancer,which can reduce tumor stage before surgery and prevent recurrence and metastasis after surgery.Effective neoadjuvant radiotherapy is one of the approaches to improve surgical resection rate in patients with diffuse gastric cancer.In this paper,the clinical application of radiotherapy for diffuse gastric cancer will be reviewed,including the selection of reasonable radiotherapy system,precise location,dose setting,application of sensitization technology and mechanism of sensitization,in addition,the prevention and treatment of neoadjuvant radiotherapy and radiotherapy complications will be introduced.