文献类型：期刊文献

中文题名：混合均匀设计效应面法优选赤芍中芍药苷的提取工艺

英文题名：Optimization of the Extraction Technology of Peoniflorin from Radix Paeoniae Rubra by Uniform Design and Response Surface Methodology

作者：彭晓霞[1];路莎莎[1];张振巍[1]

第一作者：彭晓霞

机构：[1]甘肃中医学院

第一机构：甘肃中医药大学

年份：2011

卷号：22

期号：11

起止页码：994

中文期刊名：中国药房

外文期刊名：China Pharmacy

收录：CSTPCD;;北大核心:【北大核心2008】；CSCD:【CSCD_E2011_2012】；

语种：中文

中文关键词：赤芍;芍药苷;均匀设计;效应面法;提取工艺

外文关键词：Radix Paeoniae Rubra; Paeoniflorin; Uniform design; Response surface methodology;Extraction technology

摘要：目的:优选赤芍中芍药苷的提取工艺。方法:以加水量、煎煮时间、药材浸泡时间、提取次数为考察因素,以芍药苷提取率为评价指标,采用混合均匀试验效应面法优选最佳提取工艺。结果:最佳提取工艺为加水17倍,煎煮2h,浸泡30min,提取2次。结论:采用均匀设计与效应面法相结合的方法对工艺优化更方便、更准确。
OBJECTIVE： To optimize the extraction technology of peoniflorin from Radix Paeoniae Rubra. METHODS： The extraction technology of peoniflorin was optimized by uniform design and response surface methodology using amount of water, decocting time, soak time, extracting time as factors and the extracting rate of peoniflorin as index. RESULTS： The optimal extraction technology was as follows： 17-folds water, deeocting for 2 hours, soaking for 30 rain, extracting for 2 times. CONCLUSION： Uniform design and response surface methodology is convenient and accurate for the optimization of experiment technology.